TRANSLATIONAL

Loss of an Enzyme in the Endoplasmic Reticulum—a Cell’s Transportation System—Might Play a Protective Role in Spondyloarthritis

Spondyloarthritis is a family of inflammatory diseases that affects the spine, pelvic joints, shoulders, and knees. This study demonstrated that altering the expression of ERAP1 protein may protect against arthritis.
Cell Biology Clinical Research Genetics and Genomics Immunology Molecular Biology and Biochemistry
BASIC

Isolation and Culture of Muscle Stem Cells and Progenitor Cells

The protocol describes in detail the mechanical and enzymatic dissociation of mononucleated cells from whole limb muscles and injured tibialis anterior (TA) muscles to isolate FAPs and MuSCs. Additionally, it describes an optimized method for culturing quiescent and activated FAPs and MuSCs.
Cell Biology Developmental Biology Muscle Biology Stem Cell Biology
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