Presence of co-existing anti-Sp4 autoantibodies identifies a subgroup of anti-TIF1γ-positive DM patients with lower cancer risk.

Anti-FHL1 autoantibodies in juvenile myositis is associated with V-sign rash on their chest and co-existing anti-Ro52 autoantibodies but not with adverse outcomes.

A derivative of itaconic acid, 4-octyl itaconate, inhibits immune dysregulation and organ damage in lupus mice.

NETs were detected in many organs of adult patients who died from COVID-19 complications. Compared with other SARS-CoV-2 strains, the Omicron variant was associated with decreased NET levels.

Premenopausal SLE females receiving CYC may benefit from GnRHa treatment to increase their pregnancy chances.

PGZ induces significant improvements in vascular stiffness and cardiometabolic parameters in SLE. The role of PGZ as a modulator of cardiovascular disease risk in SLE should be further explored.

The study described how the regulation of residual UBA1b translation is fundamental to VEXAS syndrome pathogenesis and contributes to disease prognosis.

This study provides some of the first and only available data about the direct relationship between FDG-PET activity and angiographic change in large-vessel vasculitis.

The study provides a new view of human neutrophil heterogeneity, with potential implications for neutrophil characterization in health and disease.

The Society for Immunotherapy of Cancer (SITC) published the first clinical practice guideline (CPG) focused on immunotherapy for nonmelanoma skin cancer (NMSC).