TRANSLATIONAL

Sex differences in neutrophil biology affect response to type I interferons and cellular metabolism

There are striking differences between men and women in their ability to respond to certain infections, predisposition to and prognosis in certain cancers, and risk for developing an autoimmune disease. However, the underlying mechanisms that drive the differences between the male and female immune system remain insufficiently characterized, especially for innate immune system cells like neutrophils.
Autoimmunity
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