NIAMS funded research has led to breakthroughs and new treatments, helping people live longer, healthier lives, and building the research foundation that drives discovery. Learn more about some of the funded research programs currently underway.
Accelerating Medicines Partnership (AMP)
The National Institutes of Health (NIH), pharmaceutical companies, and nonprofit organizations created the Accelerating Medicines Partnership® (AMP®) to develop new ways of identifying and validating promising biological targets for diagnostics and drug development. NIAMS participates in a number of AMP programs designed to accelerate the development of therapies for autoimmune diseases. For more information, see NIAMS Involvement in the Accelerating Medicines Partnership.
Back Pain Consortium (BACPAC) Research Program
The Back Pain Consortium (BACPAC) Research Program is a translational, patient-centered effort to address the need for effective and personalized therapies for chronic low back pain. It will examine biomedical mechanisms within a biopsychosocial context by using interdisciplinary methods and exploring innovative technologies. BACPAC is part of the NIH Helping to End Addiction Long-term® Initiative, or NIH HEAL Initiative®. For more information, see The Role of NIAMS in the NIH HEAL Initiative.
Environmental Influences on Child Health Outcomes (ECHO) Program
The Environmental Influences on Child Health Outcomes (ECHO) program seeks to advance knowledge in the effects of environmental exposures on child health and development. The 7-year study will support multiple, synergistic, longitudinal studies to investigate physical, chemical, biological, social, behavioral, natural and built environmental exposures. View a list of current ECHO awards. More
The NIAMS HIV/AIDS program supports and encourages observational, translational, and basic/pre-clinical research focused on how the presence or treatment of HIV/AIDS impacts various disease areas.
Molecular Transducers of Physical Activity in Humans Consortium (MoTrPAC)
The NIH Common Fund’s Molecular Transducers of Physical Activity in Humans program aims to extensively catalogue the biological molecules affected by physical activity in people, identify some of the key molecules that underlie the systemic effects of physical activity, and characterize the function of these key molecules. This molecular map will help us understand how physical activity translates into better health. View a list of NIAMS-funded MoTrPAC awards.
The Osteoarthritis Initiative (OAI) is a multicenter, longitudinal, prospective observational study of knee osteoarthritis (OA). This Initiative is a public-private partnership between the NIH and private industry that seeks to improve diagnosis and monitoring of OA and foster development of new treatments. More
Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium
The ‘Validation of Pediatric Patient Reported Outcomes in Chronic Diseases (PEPR) Consortium (U19)’ will capitalize on recent advances in the science of Patient Reported Outcomes (PROs) to assess the health of children with a variety of chronic diseases and conditions in clinical research and care settings. View a list of all NIAMS-funded PEPR awards. More
Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN)
The goal of RE-JOIN will be to define the innervation of the different articular and peri-articular tissues that collectively form the joint (including bone, cartilage, synovium, joint capsule, ligament, tendon, fascia and muscle), by sensory neurons that mediate the sensation of pain. Knowledge about the types and distribution of neurites in joint tissues will facilitate the identification of key receptors and mediators that induce pain by activating specific sensory neurons. These mediators and their receptors will provide novel targets for reducing pain. REJOIN is part of the NIH HEAL Initiative. For more information, see The Role of NIAMS in the NIH HEAL Initiative.