Ankylosing Spondylitis

What is ankylosing spondylitis? It is arthritis that affects the spine, usually producing redness, heat, swelling, and pain in the spine where it joins the pelvis.

Arthritis

Arthritis is joint inflammation that can cause stiffness or pain. Learn more about the symptoms & treatments.

Autoimmune Diseases

What are autoimmune diseases? These diseases occur when your immune cells attack your body by mistake. These diseases can affect almost any part of the body.

Autoinflammatory Diseases

What are autoinflammatory diseases? They cause your immune cells to attack your body by mistake, and can cause fever, rash, joint swelling, and more.

Behçet’s Disease

What is Behçet’s disease? It is a chronic condition that causes mouth or genital sores, and inflammation in parts of the eye.

Bursitis

What is bursitis? It is a common condition that causes swelling and pain around muscles and bones.

Giant Cell Arteritis

What is giant cell arteritis? It causes arteries in the scalp and neck to become red, hot, swollen, or painful. Arteries most affected are those in the temples.

Gout

What is gout? It is a kind of arthritis that causes painful and stiff joints. Gout is caused by the build-up of crystals of uric acid in your joints.

Hip Replacement Surgery

Hip replacement surgery removes damaged or diseased parts of a hip joint and replaces them with new, artificial parts.

Juvenile Idiopathic Arthritis (JIA)

Juvenile arthritis describes arthritis in children. Arthritis is caused by inflammation of the joints. Find out all you need to know about juvenile arthritis.

Osteoarthritis

What is osteoarthritis? It damages the slippery tissue that covers the ends of bones, causing bones to rub together, producing pain, swelling, and loss of motion.

Polymyalgia Rheumatica

What is polymyalgia rheumatica? It causes muscle pain and stiffness in the neck, shoulder, and hip, and can be accompanied by fever, weakness, and weight loss.

Psoriatic Arthritis

What is psoriatic arthritis? It can occur in people who have psoriasis (scaly red and white patches). It affects the joints and areas where tissues attach to bone.

Reactive Arthritis

What is reactive arthritis? It is caused by an infection and results in joint pain and swelling. You may also have red, swollen eyes and a swollen urinary tract.

Rheumatoid Arthritis

What is rheumatoid arthritis? It is a disease that affects multiple joints, resulting in pain, swelling, and stiffness. Tiredness and fever may also be present.

Scleroderma

Scleroderma causes patches of tight, hard skin, but can also harm your blood vessels and organs. Learn the causes and treatments of this skin disease.

Sjögren’s Syndrome

What is Sjögren’s syndrome? It is a disease that affects the glands that make moisture. It most often causes dryness in the mouth and eyes.

Systemic Lupus Erythematosus (Lupus)

Lupus is a disease where the body's defense system attacks healthy cells and tissues, causing damage to many parts of the body. Learn more about this disease.

Tendinitis

What is tendinitis? It is swelling and pain in a joint usually caused by repeated injuries to a tendon, the part of the joint that connects muscles to bones.

Selected Research Areas

Translational Genetics and Genomics Unit

Led by Dr. Michael Ombrello, the unit uses genomic approaches to understand the underlying factors of autoinflammatory and rheumatic diseases.

Arthritis and Rheumatic Disease News

Spotlight on Research | November 23, 2021

New treatment shows promise in reducing the risk of cardiovascular disease in people with lupus

Researchers have identified a potential treatment to reduce the risk of cardiovascular disease in people with systemic lupus erythematosus (SLE), a chronic autoimmune disease.
Announcement | August 19, 2020

NIH Offers Web-Based Tool to Study Gene Expression in Human Neutrophils

NIH scientists developed and recently released a free, online data query tool called NeutGX. Researchers around the world can use NeutGX to explore the genetic basis of neutrophil-mediated inflammation in autoimmune diseases, cancer, infectious diseases and other conditions.
Announcement | September 4, 2019

NIAMS Celebrates Lupus Research Progress at Fourth Annual D.C. Lupus Consortium Meeting

On May 17, 2019, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) lupus clinical research team gathered for the upcoming 25th anniversary of the natural history of systemic lupus erythematosus (SLE) protocol at the annual D.C. Lupus Consortium (DCLC) meeting. “We are here to celebrate and recognize the patients, providers, researchers and advocates who have supported lupus research at the Clinical Center over the last 25 years,” said Robert Carter, M.D., acting director of NIAMS, during his welcoming address to over 175 guests in attendance.
Last Updated: January 2022