Sarfaraz Hasni, M.D.

Staff Clinician

Head, Lupus Clinical Trials Unit

Director, Community Health Clinic

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Summary

Dr. Sarfaraz Hasni joined NIAMS in 2009 after completing his fellowship training in Clinical Rheumatology from the State University of New York at Stony Brook. After joining NIAMS he completed the NIH-Duke Masters in Clinical Research Program. His research interest in lupus is focused on new biomarker discovery and early phase proof of concept clinical trials.

He has established a collaborative network of rheumatologists, nephrologists, physiatrists and other health care providers interested in lupus clinical research in the Metropolitan DC area called the DC Lupus Consortium.

Dr. Hasni is also an active clinician and core faculty of the Rheumatology Fellowship Training Program at NIAMS. He has initiated several quality improvement processes to provide excellent clinical care to patients with lupus per current international guidelines.

In 2021, Dr. Hasni received the William G. Coleman Jr., Ph.D., Research Innovation Award for his project which aims to bolster the participation and representation of varied patient cohorts in clinical research on systemic lupus erythematosus.

Scientific Publications

Changes in cardiorespiratory function and fatigue following 12 weeks of exercise training in women with systemic lupus erythematosus: a pilot study.

Hasni S, Feng LR, Chapman M, Gupta S, Ahmad A, Munday A, Mazhar MA, Li X, Lu S, Tsai WL, Gadina M, Davis M, Chu J, Manna Z, Nakabo S, Kaplan MJ, Saligan L, Keyser R, Chan L, Chin LMK
Lupus Sci Med.
2022 Oct;
9(1).
doi: 10.1136/lupus-2022-000778
PMID: 36220328

Clinical Images: Cardiovascular magnetic resonance to detect and monitor inflammatory myocarditis in systemic lupus erythematosus.

Pamuk ON, Bandettini WP, Vargha J, Shanbhag SM, Hasni S
ACR Open Rheumatol.
2022 Feb;
4(2).
doi: 10.1002/acr2.11364
PMID: 34791837

Risk Factors for COVID-19 and Rheumatic Disease Flare in a US Cohort of Latino Patients.

Fike A, Hartman J, Redmond C, Williams SG, Ruiz-Perdomo Y, Chu J, Hasni S, Ward MM, Katz JD, Gourh P
Arthritis Rheumatol.
2021 Jul;
73(7).
doi: 10.1002/art.41656
PMID: 33455077

Correspondence on 'Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine'.

Gupta S, Nakabo S, Chu J, Hasni S, Kaplan MJ
Ann Rheum Dis.
2023 Oct;
82(10).
doi: 10.1136/annrheumdis-2020-219648
PMID: 33452005

Brief Report: Deficiency of Complement 1r Subcomponent in Early-Onset Systemic Lupus Erythematosus: The Role of Disease-Modifying Alleles in a Monogenic Disease.

Demirkaya E, Zhou Q, Smith CK, Ombrello MJ, Deuitch N, Tsai WL, Hoffmann P, Remmers EF, Takeuchi M, Park YH, Chae J, Barut K, Simsek D, Adrovic A, Sahin S, Caliskan S, Chandrasekharappa SC, Hasni SA, Ombrello AK, Gadina M, Kastner DL, Kaplan MJ, Kasapcopur O, Aksentijevich I
Arthritis Rheumatol.
2017 Sep;
69(9).
doi: 10.1002/art.40158
PMID: 28544690

Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy.

Blazkova J, Gupta S, Liu Y, Gaudilliere B, Ganio EA, Bolen CR, Saar-Dover R, Fragiadakis GK, Angst MS, Hasni S, Aghaeepour N, Stevenson D, Baldwin N, Anguiano E, Chaussabel D, Altman MC, Kaplan MJ, Davis MM, Furman D
J Immunol.
2017 Mar 15;
198(6).
doi: 10.4049/jimmunol.1601855
PMID: 28179497

Distinct Functions of Autoantibodies Against Interferon in Systemic Lupus Erythematosus: A Comprehensive Analysis of Anticytokine Autoantibodies in Common Rheumatic Diseases.

Gupta S, Tatouli IP, Rosen LB, Hasni S, Alevizos I, Manna ZG, Rivera J, Jiang C, Siegel RM, Holland SM, Moutsopoulos HM, Browne SK
Arthritis Rheumatol.
2016 Jul;
68(7).
doi: 10.1002/art.39607
PMID: 26815287

Autoreactive IgE is prevalent in systemic lupus erythematosus and is associated with increased disease activity and nephritis.

Dema B, Pellefigues C, Hasni S, Gault N, Jiang C, Ricks TK, Bonelli MM, Scheffel J, Sacré K, Jablonski M, Gobert D, Papo T, Daugas E, Illei G, Charles N, Rivera J
PLoS One.
2014;
9(2).
doi: 10.1371/journal.pone.0090424
PMID: 24587356

miR-150 promotes renal fibrosis in lupus nephritis by downregulating SOCS1.

Zhou H, Hasni SA, Perez P, Tandon M, Jang SI, Zheng C, Kopp JB, Austin H 3rd, Balow JE, Alevizos I, Illei GG
J Am Soc Nephrol.
2013 Jun;
24(7).
doi: 10.1681/ASN.2012080849
PMID: 23723424
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