The Society for Immunotherapy of Cancer (SITC) published the first clinical practice guideline (CPG) focused on immunotherapy for nonmelanoma skin cancer (NMSC).

The study provides a new view of human neutrophil heterogeneity, with potential implications for neutrophil characterization in health and disease.

This study provides some of the first and only available data about the direct relationship between FDG-PET activity and angiographic change in large-vessel vasculitis.

The study described how the regulation of residual UBA1b translation is fundamental to VEXAS syndrome pathogenesis and contributes to disease prognosis.

PGZ induces significant improvements in vascular stiffness and cardiometabolic parameters in SLE. The role of PGZ as a modulator of cardiovascular disease risk in SLE should be further explored.

Premenopausal SLE females receiving CYC may benefit from GnRHa treatment to increase their pregnancy chances.

NETs were detected in many organs of adult patients who died from COVID-19 complications. Compared with other SARS-CoV-2 strains, the Omicron variant was associated with decreased NET levels.

A derivative of itaconic acid, 4-octyl itaconate, inhibits immune dysregulation and organ damage in lupus mice.

Anti-FHL1 autoantibodies in juvenile myositis is associated with V-sign rash on their chest and co-existing anti-Ro52 autoantibodies but not with adverse outcomes.

Presence of co-existing anti-Sp4 autoantibodies identifies a subgroup of anti-TIF1γ-positive DM patients with lower cancer risk.

The FOXM1 pathway is a novel regulator of NET formation during diabetic wound healing and can be used as a therapeutic target to promote healing in DFUs. Expression of TREM1 in neutrophils is less in DFUs.

The protocol describes in detail the mechanical and enzymatic dissociation of mononucleated cells from whole limb muscles and injured tibialis anterior (TA) muscles to isolate FAPs and MuSCs. Additionally, it describes an optimized method for culturing quiescent and activated FAPs and MuSCs.