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NIAMS Pain Research

https://www.niams.nih.gov/grants-funding/niams-supported-research-programs/niams-funded-pain-research

Many of the diseases within the NIAMS research mission cause pain, disability, or disfigurement. Pain, both acute and chronic, can significantly impact mobility and quality of life. However, critical knowledge gaps remain, including: the mechanisms of pain; the outcome measures, biomarkers, and treatment options that can prevent or alleviate pain; and measures that can improve health in populations suffering from pain.

Meet the Director: Lindsey A. Criswell, M.D., M.P.H., D.Sc., National Institute of Arthritis and Musculoskeletal and Skin Diseases

https://www.niams.nih.gov/meet-director-lindsey-criswell-md-mph-dsc-national-institute-arthritis-and-musculoskeletal-and-skin

Lindsey A. Criswell, M.D., M.P.H., D.Sc., Director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), encourages researchers she supports to think outside the box. Dr. Criswell talked with NIH MedlinePlus Magazine about how diverse ideas can help us better understand conditions such as autoimmune diseases (when the immune system attacks healthy cells by mistake) and initiatives that promote diversity and inclusion in research.
CLINICAL

Genetic variants of hemophagocytic lymphohistiocytosis genes are enriched in children with systemic juvenile idiopathic arthritis

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NIAMS IRP
Familial hemophagocytic lymphohistiocytosis (HLH) is a life-threatening cytokine storm syndrome caused by recessive, loss of function variants of genes in the pathway that controls the processing of cytolytic granule processing pathway genes. Heterozygous variants in these genes contribute to a secondary form of HLH (macrophage activation syndrome, MAS) that frequently develops in children with systemic juvenile idiopathic arthritis (sJIA). To evaluate the relationship between HLH gene variation and sJIA without MAS, HLH genes were sequenced and compared between 524 patients with sJIA and 2,924 control patients.
Autoimmunity Genetics and Genomics

Late-Stage Translation of Biomedical and Behavioral Research Results in Arthritis and Musculoskeletal and Skin Diseases from Academic/Non-profit Lab to Marketplace (SBIR [R43/R44] Clinical Trial Not Allowed)

https://www.niams.nih.gov/grants-funding/niams-current-funding-opportunities/late-stage-translation-biomedical-and-behavioral

This funding opportunity ( PAR-23-032) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that translate technology and therapeutic innovations from academic and other non-profit research sectors to the marketplace to advance the development of diagnostic and prevention tools or treatments for musculoskeletal, rheumatic or skin

Dr. Lindsey Criswell Named as New NIAMS Director

https://www.niams.nih.gov/newsroom/announcements/dr-lindsey-criswell-named-new-niams-director

Lindsey A. Criswell, M.D., M.P.H., D.Sc., has been named director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS). Dr. Criswell is currently vice chancellor of research at the University of California, San Francisco (UCSF). She is a professor of rheumatology and a professor of orofacial sciences at UCSF. She expects to join NIH in early 2021, as the third director in the history of NIAMS. “Dr. Criswell has rich experience as a clinician, researcher and administrator. Her ability to oversee the research program of one of the country’s top research-intensive medical schools, and her expertise in

Discussing Bone, Muscle, Skin, & Autoimmune Diseases: Info for American Indians, Alaska Natives

https://www.niams.nih.gov/newsroom/featured/discussing-bone-muscle-skin-autoimmune-diseases-info-american-indians-alaska

A conversation between Dr. David R. Wilson, director of the NIH Tribal Health Research Office, and Dr. Lindsey A. Criswell, director of NIAMS, about information and resources for American Indians and Alaska Natives related to bone, muscle, skin, and autoimmune diseases. Watch the video on YouTube. Transcript Dave Wilson: Hello, my name is Dr. Dave Wilson. I am a member of the Navajo Nation, and I am also the Director of the Tribal Health Research Office, also known as THRO, here at the National Institutes of Health. Today I am joined by my colleague Dr. Lindsay Criswell, who is the

Typically materials from NIAMS that are more than 5 years old will be archived.

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