Our group studies the outcomes of many important orthopaedic conditions. We are using large clinical databases to study rare femur fractures, uncommon hip infections, and novel fracture treatments. The goal is to provide clinical insight into conditions that cannot be studied in traditional clinical studies.
We are also interested in atypical fractures of the femur. We are currently recruiting for a clinical trial in which we screen long-term bisphosphonate users for the radiographic markers of atypical femur fractures. The study is designed to determine who is at risk, and to further our understanding of the biology of these rare fractures.
We are also interested in a rare bone disease called melorheostosis. Patients with melorheostosis develop slow growing bone lesions for unknown reasons. A peculiar anatomic distribution pattern similar to dermatomes is often seen.
Wang Z, Bhattacharyya T. Trends of non-union and prescriptions for non-steroidal anti-inflammatory drugs in the United States, 1993-2012. Acta Orthop. 2015 Mar 12:1-6. [Epub ahead of print]
Wang Z, Ward MM, Chan L, Bhattacharyya T. Adherence to oral bisphosphonates and the risk of subtrochanteric and femoral shaft fractures among female medicare beneficiaries. Osteoporos Int. 2014 Aug;25(8):2109-16. doi: 10.1007/s00198-014-2738-x. Epub 2014 May 21.
Chen F, Wang Z, Bhattacharyya T. Absence of femoral cortical thickening in long-term bisphosphonate users: implications for atypical femur fractures. Bone. 2014 May;62:64-6. doi: 10.1016/j.bone.2014.01.011. Epub 2014 Jan 25.