The principal mission of the Light Imaging Section is to give NIAMS scientists access to state-of-the-art equipment and to offer training and assistance in the acquisition and analysis of high quality scientific images by light microscopy. Furthermore, we use light microscopy and other techniques to elucidate poorly understood aspects of skeletal muscle cell biology, i.e. the organization of muscle microtubules and their role in muscle diseases. We also strive to apply new modalities of light microscopy to the quantitative analysis of skeletal muscle pathologies.
The Light Imaging Section is equipped for widefield and confocal microscopy, multi-photon microscopy, TIRF, high-throughput live cell imaging, and slide scanning. See full list of instruments available.
For access to instruments and more information, contact Dr. Randazzo (firstname.lastname@example.org) or Ms. Kenea (email@example.com).
Core Research Facilities
Labs at the NIAMS are supported by the following state-of-the-art facilities and services:
Image & Media Gallery
The Office of Science and Technology (OST) within the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is recruiting for a Staff Scientist position to be assigned to the Light Imaging Section (LIS).
A successful candidate is expected to be highly skilled in imaging techniques ranging from widefield, confocal, and superresolution microscopy to total internal reflection fluorescence microscopy, lattice lightsheet microscopy, high throughput live cell imaging, spatial transcriptomics, automated histology slide scanning, and advanced image quantification, including analysis. He/She will be required to establish the most appropriate protocol for multiplexed imaging of tissue sections as well as fixed and live cells. The candidate will be responsible for assisting in the development of research plans with the NIAMS investigators and offering advice on the best imaging design, the most appropriate imaging techniques, and the corresponding instrumentation. He/She will provide training for the independent use of state-of-the-art imaging instruments and extend the interaction with the core facility users after training to assist them in the post-acquisition analysis by suggesting the appropriate software tools and processing pipelines to ensure a conscious approach to data presentation. The candidate will also be required to assist core users with assembling micrographs for publications.
The candidate will have or will be able to establish a solid network with other microscopy core facilities and microscopy experts both inside and outside the NIH. The candidate will also need to be up-to-date with the latest technological advancements in the microscopy field and have a strategic vision for the future of the core as he/she will be expected to provide advice to institute leadership in proposing the acquisition of new instruments and techniques, when these may represent a significant step forward for the LIS.
Applicants should have a doctoral degree in cell biology or a related field and at least five years of postdoctoral experience. A record of peer-reviewed publications is required. The successful candidate should have strong communication skills and the ability to work collaboratively. Interested individuals should send a cover letter, curriculum vitae, summary of research experience, list of accomplishments, research interests and goals, three publications or reprints, and three letters of reference electronically to firstname.lastname@example.org.
Salary is commensurate with research experience and accomplishments.
Dr. Massimo Gadina
Office of Science and Technology
Intramural Research Program, NIAMS
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