Aster Kenea, B.S.

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Summary

Aster Kenea obtained her Bachelor's in Biological Science from the University of Maryland Baltimore County. She joined the Light Imaging Section at NIAMS as a post-baccalaureate fellow and trained for two years.

Her research focused on understanding the role of dystrophin in muscle pathology. She investigated the organization of the Golgi complex and microtubules in skeletal muscle fibers, specifically as it relates to Duchenne muscular dystrophy. 

Aster's expertise includes using microscopy techniques and various imaging instruments to understand biological processes.

Scientific Publications

Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements.

Oddoux S, Zaal KJ, Tate V, Kenea A, Nandkeolyar SA, Reid E, Liu W, Ralston E
J Cell Biol.
2013 Oct 28;
203(2).
doi: 10.1083/jcb.201304063
PMID: 24145165

Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle.

Randazzo D, Khalique U, Belanto JJ, Kenea A, Talsness DM, Olthoff JT, Tran MD, Zaal KJ, Pak K, Pinal-Fernandez I, Mammen AL, Sackett D, Ervasti JM, Ralston E
Hum Mol Genet.
2019 Apr 1;
28(7).
doi: 10.1093/hmg/ddy418
PMID: 30535187

Corrigendum: Persistent upregulation of the β-tubulin tubb6, linked to muscle regeneration, is a source of microtubule disorganization in dystrophic muscle.

Randazzo D, Khalique U, Belanto JJ, Kenea A, Talsness DM, Olthoff JT, Tran MD, Zaal KJ, Pak K, Pinal-Fernandez I, Mammen AL, Sackett D, Ervasti JM, Ralston E
Hum Mol Genet.
2019 Jun 1;
28(11).
doi: 10.1093/hmg/ddz035
PMID: 30753428

Misplaced Golgi Elements Produce Randomly Oriented Microtubules and Aberrant Cortical Arrays of Microtubules in Dystrophic Skeletal Muscle Fibers.

Oddoux S, Randazzo D, Kenea A, Alonso B, Zaal KJM, Ralston E
Front Cell Dev Biol.
2019;
7().
doi: 10.3389/fcell.2019.00176
PMID: 31620435
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