A type of skin cell called a dermal fibroblast can make an antimicrobial compound called cathelicidin in response to infection by acne-causing bacteria.

Human skin is home to diverse ecosystems including bacteria, viruses, and fungi. These microbial communities comprise hundreds of species and are collectively known as the skin microbiome.

In her December 2021 letter, NIAMS Director Dr. Lindsey Criswell discussed the launch of the Accelerating Medicines Partnership® Autoimmune and Immune-Mediated Diseases (AMP® AIM) program. This new initiative builds upon the progress of the prior AMP RA/SLE project, which greatly advanced our understanding of the mechanisms that drive disease in rheumatoid arthritis (RA) and lupus.

The NIAMS K Forum brings together clinician-scientists with a NIAMS K08 or K23 award.

A conversation between Dr. David R. Wilson, director of the NIH Tribal Health Research Office, and Dr. Lindsey A. Criswell, director of NIAMS, about information and resources for American Indians and Alaska Natives related to bone, muscle, skin, and autoimmune diseases. Watch the video on YouTube. Transcript Dave Wilson: Hello, my name is Dr. Dave Wilson. I am a member of the Navajo Nation, and I am also the Director of the Tribal Health Research Office, also known as THRO, here at the National Institutes of Health. Today I am joined by my colleague Dr. Lindsay Criswell, who is the

Researchers published a proof-of-principle paper in the journal Science Immunology demonstrating just how precision medicine for inflammatory skin rashes might work.

A treatment for severe skin inflammation that works well in lean mice made the condition worse in obese mice because of immune-cell changes associated with obesity.

The Health Disparities in Osteoarthritis (OA) workshop brought together OA investigators with others who have expertise in health disparities to exchange ideas regarding how/why disparities in OA treatment and care exist and how they can be addressed. Panelists and speakers highlighted mechanisms through which behavioral and biomedical science integration can lead to better health in OA.

NIAMS organized a roundtable to engage stakeholders to discuss challenges, gaps, and opportunities regarding regenerative medicine approaches for cartilage preservation and restoration in knee OA and where and how NIAMS could play a role and move the field forward.