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Amping Up Our Investment in Autoimmune Disease Research

https://www.niams.nih.gov/about/about-the-director/letter/amping-up-our-investment-in-autoimmune-disease-research

Dear Colleagues, Today, the National Institutes of Health, the Foundation for the National Institutes of Health (FNIH), eight pharmaceutical companies and five non-profit organizations have partnered to further our understanding of the cellular and molecular disease pathways in autoimmune and immune-mediated diseases.

Researchers identify cellular pathway that regulates inflammatory hair loss

https://www.niams.nih.gov/newsroom/spotlight-on-research/researchers-identify-cellular-pathway-regulates-inflammatory-hair

NIH researchers reveal new insights about the relationship between hair and hair follicles and the skin’s immune system.

New Opportunities for Advancing Pain Science

https://www.niams.nih.gov/about/about-the-director/letter/new-opportunities-for-advancing-pain-science

Dear Colleagues, From the Hippocratic corpus, the author writes, “I consider the responsibility of medicine to be to entirely relieve the suffering of the sick and to blunt the extremities of disease” (The Art 3.4-7)1. Note that despite the acknowledgment that disease may only be blunted, in promoting health it is our duty to relieve suffering wherever possible.

Dr. Janelle Hauserman is the NIAMS IRP Training Director. Before her current position, she was a postdoc in NINDS and then served as a Scientific Program Manager in the NIAMS Office of Scientific Operations.

Genetic Sequencing Solves Drug Reaction Mystery

https://www.niams.nih.gov/genetic-sequencing-solves-drug-reaction-mystery

A researcher from Stanford University asked IRP investigator Michael Ombrello, M.D., to help her team follow a new lead in the mystery of why some patients with a rare inflammatory condition called Still’s disease were coming down with a life-threatening lung ailment.

Accelerating Medicines Partnership® Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP® RA/SLE) Program

https://www.niams.nih.gov/grants-funding/funded-research/accelerating-medicines/RA-SLE

The Accelerating Medicines Partnership® Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP® RA/SLE) program launched in 2014 as one of the original components of the Accelerating Medicines Partnership (AMP).

A New View of How Muscles Move

https://www.niams.nih.gov/new-view-how-muscles-move

Using images of cells from mice, Dr. Glancy and his lab showed that myofibrils are actually not made of individual pieces lying side by side. Instead, they actually have little connections where the tubes branch off or split and connect to adjacent ones.

Michelle Millwood, BSN

https://www.niams.nih.gov/about/directory/michelle-millwood-bsn

Michelle Millwood, RN, works on research involving Systemic Juvenile Idiopathic Arthritis (sJIA) and Juvenile Dermatomyositis (JDM) studies conducted at the NIH.

Kang Yu, Ph.D.

https://www.niams.nih.gov/about/directory/kang-yu-phd

Dr. Yu’s current research focuses on how super-enhancers and non-coding RNA modulate immune regulator genes and the implications in lymphocyte development, differentiation, and activation.

What Our Proteins Can Tell Us About Autoimmune Diseases

https://www.niams.nih.gov/what-our-proteins-can-tell-us-about-autoimmune-diseases

Adeline Chin, a postbaccalaureate research fellow, is searching for proteins present at abnormally high or low levels in the blood of kids with a rare autoimmune illness.

New Web Application to Study Cellular Responses to Glucocorticoids

https://www.niams.nih.gov/new-web-application-study-cellular-responses-glucocorticoids

Although the drugs have been around for more than 70 years, scientists have a poor understanding of how glucocorticoids regulate the immune system and the mechanisms by which they cause toxicity in different organs.

NIAMS Reportable Events Requirements and Guidelines for Investigators Conducting NIAMS-Funded Clinical Research Studies

https://www.niams.nih.gov/grants-funding/conducting-clinical-trials/clinical-trial-policies-guidelines-and-templates/data-1

A. Introduction These requirements and guidelines created by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) detail the safety reporting processes that investigators are required to follow when conducting NIAMS-supported clinical research studies. These studies include clinical trials and other types of clinical research studies e.g., observational

Scientific Peer Review

https://www.niams.nih.gov/grants-funding/scientific-peer-review

An overview of the Scientific Review Branch (SRB). SRB is responsible for the initial scientific and technical merit review of grant applications submitted in response to NIAMS requests for applications, program announcements with special receipt, referral, and/or review considerations, career development (K) awards, R13 conference grants, clinical trials, and other special initiatives.

Engineered cartilage produces anti-inflammatory drug

https://www.niams.nih.gov/engineered-cartilage-produces-anti-inflammatory-drug

NIAMS Forum for Clinical Mentored K Awardees - December 2020

https://www.niams.nih.gov/newsroom/roundtable/niams-forum-clinical-mentored-k-awardees-december-2020

NIAMS held its first K Forum in 2012. Based on the positive feedback received from participants, NIAMS convened subsequent meetings annually. T

Research: MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23

https://www.niams.nih.gov/newsroom/featured/new-research-published-journal-immunity

In a recent study in the journal Immunity, NIAMS investigators provide new insight into mechanisms of disease by the adaptive immune system.

Patchy Skin - Vitiligo Explained

https://www.niams.nih.gov/patchy-skin-vitiligo-explained

Dr. Kaplan Receives GPP Outstanding Mentor Award

https://www.niams.nih.gov/labs/dr-kaplan-receives-gpp-outstanding-mentor-award

We are delighted to announce that Mariana Kaplan, M.D., Deputy Scientific Director of NIAMS and Chief of the Systemic Autoimmunity Branch, has received a 2021 Graduate Partnership Program Outstanding Mentor Award. This award recognizes outstanding mentors for their leadership and dedication to their graduate students.