Long-running fractures study doubles as a bountiful women’s health data source
https://www.niams.nih.gov/long-running-fractures-study-doubles-bountiful-womens-health-data-source
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Scleroderma Genomics and Health Disparities Unit
https://www.niams.nih.gov/labs/scleroderma-genomics-and-health-disparities-lab
The Scleroderma Genomics and Health Disparities Unit is focused on unraveling genetic risk by using genomic technologies and dissecting the mechanisms of transcriptional regulation in order to comprehend autoimmune, fibrotic, and health disparity conditions.
Lupus Genomics and Global Health Disparities Unit
https://www.niams.nih.gov/labs/lewandowski-lab
Dr. Lewandowski leads a team of scientists studying systemic lupus erythematosus patients in populations around the globe. Her research focuses on genetic drivers of severe disease and inflammation in diverse cohorts worldwide.
Osteoporosis
https://www.niams.nih.gov/health-topics/osteoporosis
What is osteoporosis? Osteoporosis is a disease that causes bones to become weak and brittle. This increases your risk of broken bones (fractures). Osteoporosis is a “silent” disease because you may not have symptoms. You may not even know you have the disease until you break a bone. Breaks can occur in any bone but happen most often in: Hip bones. Vertebrae in the spine. Wrist. You can take steps to help prevent osteoporosis and broken bones by: Doing weight-bearing exercises, such as walking or dancing, and lifting weights. Not drinking too much alcohol. Quitting smoking, or not starting if
Workshop Explores Strategies to Tackle Health Disparities in Osteoarthritis
https://www.niams.nih.gov/workshop-explores-strategies-tackle-health-disparities-osteoarthritis
A recent 2-day NIH workshop aimed to better understand health disparities in caring for and treating people with osteoarthritis (OA) and the role played by social determinants of health. NIAMS, NIA and NIMHD sponsored the event.
VEXAS Syndrome More Common Than Realized
https://www.niams.nih.gov/vexas-syndrome-more-common-realized
In 2020, a team of NIH researchers reported the discovery of a rare and often-deadly inflammatory disorder, which they named VEXAS. Affected people have varying symptoms that can include anemia, recurrent fevers, painful rashes, blood clots, and shortness of breath.
Raynaud’s Phenomenon
https://www.niams.nih.gov/health-topics/raynauds-phenomenon
What is Raynaud’s phenomenon? Raynaud’s phenomenon is a condition that causes the blood vessels in the hands and feet to narrow, decreasing blood flow. When this happens, parts of the body—usually the fingers and toes—become cold and numb, and change color (usually, to white or blue). An attack usually happens from exposure to cold or stress.
Ichthyosis
https://www.niams.nih.gov/health-topics/ichthyosis
What is ichthyosis? Ichthyosis is a group of skin disorders. It leads to dry, itchy skin that appears scaly, rough, and red. The symptoms can range from mild to severe. Ichthyosis can affect only the skin, but sometimes the disease can affect internal organs, too.
Autoinflammatory Diseases
https://www.niams.nih.gov/health-topics/autoinflammatory-diseases
What are autoinflammatory diseases? Autoinflammatory diseases refer to problems with the immune system, which usually fights off viruses, bacteria, and infection. The problem causes your immune cells to attack your body by mistake. This can cause swelling that produces fever, rash, joint swelling, or serious buildup of a blood protein in your organs.
Mariana J. Kaplan, M.D.
https://www.niams.nih.gov/about/directory/mariana-j-kaplan-md
Dr. Kaplan’s research focuses on identifying the molecular mechanisms that promote the initiation and perpetuation of perturbed immune responses and the development of organ damage and premature vascular disease in systemic autoimmunity.
Yongquan Luo, Ph.D.
https://www.niams.nih.gov/about/directory/yongquan-luo-phd
Dr. Luo is a biologist in the Pediatric Translational Research Branch. He is pursuing studies of mutation of gene WHAMM on pathogenesis in axial spondyloarthritis using patient derived hiPSCs and CRISPR/Cas9 technologies.
Translational Genetics and Genomics Section
https://www.niams.nih.gov/labs/ombrello-lab
Led by Dr. Michael Ombrello, the section uses genomic approaches to understand the underlying factors of autoinflammatory and rheumatic diseases.