Summary
Paul Panipinto, Ph.D., completed his undergraduate studies at the University of Washington's Molecular, Cellular, and Developmental Biology program. He then started work as a research scientist in the lab of Dr. Erika Noss at the Division of Rheumatology. There, he worked on a variety of projects related to fibroblast biology, including inflammatory signaling mechanisms in platelet-derived growth factor receptors, the identification of pathogenic subsets of fibroblasts in osteo- and rheumatoid arthritis (RA), and inflammatory mechanisms of inflammatory bowel disease.
Dr. Panipinto's work in Dr. Noss's lab developed his interest in furthering his education, and from there, he joined the lab of Dr. Salah Ahmed at Washington State University's College of Pharmacy and Pharmaceutical Science. His work included identifying the extracellular sulfatase Sulf-2's participation in TNFα mediated signaling in RA and investigations into the mechanism of inhibition of several small molecule kinase inhibitors.
Dr. Panipinto's F-31-funded thesis project focused on inhibiting the kinase TAK-1, which sits at the nexus of the NF-κB and MAPK pathways.
Research Statement
Dr. Panipinto's research at the NIH focuses on systemic juvenile arthritis and adult-onset Still's disease. His particular interest is innate immunity and mechanisms of inflammation in rare genetic disease variants.
Scientific Publications
Education
University of Washington
B.S. in Cellular and Molecular Biology (2014-2017)
Washington State University
Ph.D. in Pharmaceutical Science and Molecular Medicine (2019-2024)
Experience
Research Scientist
University of Washington Division of Rheumatology (2017-2019)
