Norio Hanata, M.D., Ph.D., Systemic Autoimmunity Branch, NIAMS

Contact Information

Summary

Norio Hanata, M.D., Ph.D., is a board-certified rheumatologist (Japan College of Rheumatology) and a postdoctoral visiting fellow in the Systemic Autoimmunity Branch at NIAMS.

Dr. Hanata received his M.D. from Niigata University and his Ph.D. from the University of Tokyo. After serving as faculty in the Department of Allergy and Rheumatology at the University of Tokyo, he joined NIAMS in 2021.

Research Statement

Dr. Hanata studies the pathogenic roles of neutrophils in systemic autoimmune diseases. His current work aims to understand the mechanisms of neutrophil-driven pathology.

Scientific Publications

The circadian clock gene BMAL1 modulates autoimmunity features in lupus.

Nakabo S, Sandoval-Heglund D, Hanata N, Brooks S, Hoffmann V, Zhang M, Ambler W, Manna Z, Poncio E, Hasni S, Islam S, Dell'Orso S, Kaplan MJ

Front Immunol.

2024;

15().

doi: 10.3389/fimmu.2024.1465185

PMID: 39664388

The role of neutrophil extracellular traps in inflammatory rheumatic diseases.

Hanata N, Kaplan MJ

Curr Opin Rheumatol.

2025 Jan 1;

37(1).

doi: 10.1097/BOR.0000000000001054

PMID: 39258603

Serum extracellular traps associate with the activation of myeloid cells in SLE patients with the low level of anti-DNA antibodies.

Hanata N, Ota M, Tsuchida Y, Nagafuchi Y, Okamura T, Shoda H, Fujio K

Sci Rep.

2022 Nov 1;

12(1).

doi: 10.1038/s41598-022-23076-1

PMID: 36319843

Serum Amphiregulin and Heparin-Binding Epidermal Growth Factor as Biomarkers in Patients with Idiopathic Inflammatory Myopathy.

Hanata N, Nagafuchi Y, Sugimori Y, Kobayashi S, Tsuchida Y, Iwasaki Y, Shoda H, Fujio K

J Clin Med.

2021 Aug 22;

10(16).

doi: 10.3390/jcm10163730

PMID: 34442026

Immature platelet levels correlate with disease activity and predict treatment response of thrombocytopenia in lupus patients.

Hanata N, Shoda H, Kono M, Komai T, Natsumoto B, Tsuchida Y, Tsuchiya H, Nagafuchi Y, Taoka K, Kurokawa M, Fujio K

Lupus.

2021 Oct;

30(11).

doi: 10.1177/09612033211034233

PMID: 34304626

Peptidylarginine Deiminase 4 Promotes the Renal Infiltration of Neutrophils and Exacerbates the TLR7 Agonist-Induced Lupus Mice.

Hanata N, Shoda H, Hatano H, Nagafuchi Y, Komai T, Okamura T, Suzuki A, Gunarta IK, Yoshioka K, Yamamoto K, Fujio K

Front Immunol.

2020;

11().

doi: 10.3389/fimmu.2020.01095

PMID: 32655553

Education

Niigata University School of Medicine, Niigata, Japan.
M.D.

Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Ph.D.

Experience

Assistant Professor
Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Postdoctoral Fellow
Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Clinical Fellow
Department of Allergy and Immunological Diseases, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.

Residency
Toranomon Hospital, Tokyo, Japan.

Norio Hanata, M.D., Ph.D.

Postdoctoral Fellow (Visiting)

Systemic Autoimmunity Branch