Dr. Natasha Hill is a research fellow in the Cutaneous Development and Carcinogenesis Section of the Dermatology Branch. She has presented her research at numerous national and international meetings. And has received awards for her work in both the iron metabolism field and skin cancer field.
Dr. Hill’s current research uses genomic and proteomic techniques to investigate the pathobiology of Merkel cell carcinoma (MCC), a neuroendocrine skin cancer that predominantly occurs in elderly and immunosuppressed populations. MCC is a rare but aggressive cancer, which is need of effective treatments for advanced disease. Her current project identifies genomic structural variants using high-density array Comparative Genomic Hybridization (aCGH) and Nanostring copy number variant technologies. Following variant validation, she will explore the role of implicated target genes in the development and progression of MCC, such as studying the role of the Golgi apparatus in MCC. By elucidating the Golgi mechanisms that promote survival pathways, she hopes to identify therapeutic targets and development novel therapies for MCC.