Jungmin Han, Ph.D.

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Contact Information

Summary

Jungmin Han, Ph.D., studied mathematics and statistics for her undergraduate degrees and received her doctorate degree in mathematics from the University of Auckland in New Zealand. She moved to the U.S. to pursue her research career as a postdoctoral fellow in the Laboratory of Biological Modeling at the National Institute of Diabetes and Digestive and Kidney Diseases. Currently, Dr. Han is a research fellow in the Cutaneous Microbiome and Inflammation Section at the National Institute of Arthritis and Musculoskeletal and Skin Diseases.
 

Research Statement

During her graduate studies, Dr. Han focused on the modeling and prediction of calcium dynamics in various cell types using ordinary differential equations and bifurcation analyses of dynamical systems. As a postdoctoral fellow, she focused on using mathematical models to gain insights into various biological systems, including developmental gene regulatory networks of the blastoderm embryo of D. melanogaster, the pathology of liver diseases, calcium dynamics in mitochondria-associated ER membranes, and the epidemic spread of SARS-CoV-2. 

Dr. Han’s research interests lie in the fields of computational biology and the skin microbiome. Using advanced genomic sequencing techniques and bioinformatics tools, she aims to understand the underlying mechanisms of host-skin microbe interactions and investigate the characteristics of skin microbial communities associated with autoimmune skin disorders.

Scientific Publications

Restoration of the human skin microbiome following immune recovery after hematopoietic stem cell transplantation.

Che Y, Han J, Harkins CP, Hou P, Conlan S, Deming C, Amirkhani A, Bingham MA, Holmes CJ, Englander H, Shen Z, NISC Comparative Sequencing Program, Castelo-Soccio L, Dimitrova D, Kanakry JA, Bergerson JRE, Notarangelo LD, Pittaluga S, Zhao C, Dell'Orso S, Pai SY, Hickstein DD, Holland SM, Brownell I, Nagao K, Gonzalez CE, Shah NN, Freeman AF, Su HC, Segre JA, Kong HH
Cell Host Microbe.
2025 Aug 13;
33(8).
doi: 10.1016/j.chom.2025.07.002
PMID: 40730159

Skin Microbiome Shifts Associated with Elevated Squamous Cell Carcinoma Risk.

Saheb Kashaf S, Higuchi H, Han J, Conlan S, Azin M, Guennoun R, Smith SS, Oliver-Garcia VS, Sorour I, Yu CT, Zeng Y, Segre JA, Kong HH, Demehri S
J Invest Dermatol.
2026 Jan;
146(1).
doi: 10.1016/j.jid.2025.06.1590
PMID: 40683337

Exploring the Skin Microbiome in Central Centrifugal Cicatricial Alopecia.

Firek A, Hou P, Han J, Holmes CJ, Suh G, Frey C, Kong HH, Castelo-Soccio L
JAMA Dermatol.
2025 Mar 1;
161(3).
doi: 10.1001/jamadermatol.2024.5421
PMID: 39813050

Longitudinal multi-omics analyses of the gut-liver axis reveals metabolic dysregulation in hepatitis C infection and cirrhosis.

Ali RO, Quinn GM, Umarova R, Haddad JA, Zhang GY, Townsend EC, Scheuing L, Hill KL, Gewirtz M, Rampertaap S, Rosenzweig SD, Remaley AT, Han JM, Periwal V, Cai H, Walter PJ, Koh C, Levy EB, Kleiner DE, Etzion O, Heller T
Nat Microbiol.
2023 Jan;
8(1).
doi: 10.1038/s41564-022-01273-y
PMID: 36522461

Predicting cancer immunotherapy response from gut microbiomes using machine learning models.

Liang H, Jo JH, Zhang Z, MacGibeny MA, Han J, Proctor DM, Taylor ME, Che Y, Juneau P, Apolo AB, McCulloch JA, Davar D, Zarour HM, Dzutsev AK, Brownell I, Trinchieri G, Gulley JL, Kong HH
Oncotarget.
2022;
13().
doi: 10.18632/oncotarget.28252
PMID: 35875611

Associations of GlycA and high-sensitivity C-reactive protein with measures of lipolysis in adults with obesity.

Levine JA, Han JM, Wolska A, Wilson SR, Patel TP, Remaley AT, Periwal V, Yanovski JA, Demidowich AP
J Clin Lipidol.
2020 Sep-Oct;
14(5).
doi: 10.1016/j.jacl.2020.07.012
PMID: 32863171

A mathematical model of calcium dynamics: Obesity and mitochondria-associated ER membranes.

Han JM, Periwal V
PLoS Comput Biol.
2019 Aug;
15(8).
doi: 10.1371/journal.pcbi.1006661
PMID: 31437152

On the dynamical structure of calcium oscillations.

Sneyd J, Han JM, Wang L, Chen J, Yang X, Tanimura A, Sanderson MJ, Kirk V, Yule DI
Proc Natl Acad Sci U S A.
2017 Feb 14;
114(7).
doi: 10.1073/pnas.1614613114
PMID: 28154146

Education

University of Auckland
Ph.D., Mathematics (2016)

University of Auckland
Master's, Applied Mathematics (2013)

University of Auckland 
Bachelor's (Hon), Applied Mathematics (2012)

University of Auckland 
Bachelor's, Science (2011)

Experience

Postdoctoral Fellowship
NIDDK/NIH (2017-2021)

Pre-doctoral Fellowship 
NIDDK/NIH (2016-2017)

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