Contact Information
Summary
Gyeongmin Kim, Ph.D., received her doctoral degree in the Department of Molecular Immunology from Ewha Womans University, Seoul, Korea, in 2023. She joined the Systemic Autoimmunity Branch at the NIAMS as a postdoctoral fellow in 2024, where she works on the pathogenesis of autoinflammatory or autoimmune conditions in systemic lupus erythematosus (SLE).
Previously, Dr. Kim worked on osteoimmunology and bone-related diseases, focusing on the molecular interactions with osteoclasts (bone-resorbing), osteoblasts (bone-forming), chondrocytes, and immune cells in the joint. She studied the catabolic regulator of chondrocytes, which accelerates articular cartilage destruction and emphasizes the ‘osteoclast–chondrocyte crosstalk’ in osteoarthritis (OA) pathogenesis. Furthermore, her thesis demonstrated the effect of a promising DMOAD (disease-modifying OA drug).
Expanding on her dissertation work, Dr. Kim focused on translational research, especially macrophage plasticity and suppressing inflammation in inflammatory disease models such as the lipopolysaccharide (LPS)-induced sepsis model, the cecal ligation and puncture (CLP) model, and the inflammatory bowel disease (IBD) mouse model.
Research Statement
Protein citrullination is a process catalyzed by a family of calcium-dependent enzymes called peptidylarginine deiminases (PADs). Five isozymes (PAD1–4 and PAD6) have unique tissue localization and overlapping substrates and are involved in various physiological processes, including immune responses, cell signaling, and gene expression regulation.
Dr. Gyeongmin Kim studies the pathogenesis of citrullinated proteins generated by PADs in systemic lupus erythematosus (SLE). Specifically, she works on how abnormal protein citrullination and aberrant immune responses to citrullinated antigens induce innate and adaptive immune dysregulation and organ damage. She is interested in elucidating the mechanisms that efficiently suppress the PAD activity in autoimmune diseases.
Scientific Publications
Education
Ewha Womans University
Postdoc Fellow, Molecular Immunology (2024)
Ewha Womans University
Ph.D., Molecular Immunology (2023)
Ewha Womans University
B.S., Life science (2017)
Experience
Postdoctoral Fellowship
National Institutes of Health, NIAMS (2024 - Present)
Postdoctoral Fellowship
Ewha Womans University, Korea (2024)
Graduate Student
Ewha Womans University, Korea (2023)