Fnu Neha, Ph.D.

Summary

Dr. Neha earned her PhD from the National Institute of Immunology, New Delhi, where she studied Vitamin D receptor (VDR) signaling in metabolic regulation. She showed that micronutrient-dependent signaling drives systemic and tissue-specific adaptation at weaning, and that loss of VDR disrupts energy homeostasis and skeletal muscle metabolic flexibility.

Research Statement

Skeletal muscle regeneration is sustained throughout life by a dedicated population of adult muscle stem cells. However, this regenerative capacity progressively declines with aging and is profoundly compromised in muscular dystrophies. Dr. Neha's research aims to delineate the cell-intrinsic alterations in metabolic, epigenetic, and transcriptional programs within muscle stem cells, as well as the extrinsic changes in the surrounding niche, that collectively drive these age-associated impairments. 
By integrating the study of intrinsic regulatory networks with microenvironmental remodeling, she seeks to identify therapeutic strategies to enhance regenerative capacity and preserve skeletal muscle homeostasis.

Scientific Publications

Vitamin D receptor signalling regulates the diet-driven metabolic shift during weaning.

Jawla N, Khare S, Yadav N, Nanda RK, Arimbasseri GA
Mol Metab.
2025 Jul;
97().
doi: 10.1016/j.molmet.2025.102158
PMID: 40294701

Lack of vitamin D signalling shifts skeletal muscles towards oxidative metabolism.

Das A, Jawla N, Meena V, Gopinath SD, Arimbasseri GA
J Cachexia Sarcopenia Muscle.
2024 Feb;
15(1).
doi: 10.1002/jcsm.13378
PMID: 38041597

Inherent metabolic preferences differentially regulate the sensitivity of Th1 and Th2 cells to ribosome-inhibiting antibiotics.

Jawla N, Kar R, Patil VS, Arimbasseri GA
Immunology.
2025 Jan;
174(1).
doi: 10.1111/imm.13860
PMID: 39263985

Education

National Institute of Immunology, New Delhi, India 
Ph.D. in Life Science (2018-2025)

Banaras Hindu University, Varanasi, India 
M.Sc. in Microbiology (2015-2017)

Experience

Visiting Fellow, NIAMS, NIH (2025 - present)

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