Displaying 501 - 520 of 1039 results
The NIH Loan Repayment Program (LRP)
https://www.niams.nih.gov/grants-funding/nih-loan-repayment-program-lrp
The National Institutes of Health Loan Repayment Program (LRP) is designed to recruit and retain highly qualified health professionals into biomedical or biobehavioral research careers.
Travis Kinder, Ph.D.
https://www.niams.nih.gov/about/directory/travis-kinder-phd
Dr. Kinder conducts basic and translational research on myositis and genetic muscle diseases. His goals are to discover fundamental mechanisms of autoimmunity and muscle biology and to develop novel therapeutics for myositis at the NIH.
IRP Scientists Sound Off in Three-Minute Talks
https://www.niams.nih.gov/irp-scientists-sound-three-minute-talks
Nandu Saravanan, B.S.
https://www.niams.nih.gov/about/directory/nandu-saravanan-bs
Nandu Saravanan is a Postbaccalaureate Fellow in the Clinical and Investigative Orthopedics Surgery Unit at the NIAMS. He studies the molecular mechanisms of the rare bone disease melorheostosis using patient-derived fibroblasts and iPSCs.
Ridhi Patil, B.S.
https://www.niams.nih.gov/about/directory/ridhi-patil-bs
Ridhi Patil is a postbac in the Intramural NIAID Research Opportunities (INRO) program. Under Dr. Luis Franco, she works on generating glucocorticoid (GC) nanobody complexes to target GC molecules to specific cell types, beginning with CD4 T-cells.
CLINICAL
Inflammatory Pathways Are Activated in VEXAS Hematopoietic Stem Cells
According to the report, mutations of UBA1 in hematopoietic stem cells appear to cause abnormal inflammation and myeloid predominance in VEXAS syndrome.
Autoimmunity
Clinical Research
Computational Biology
Epidemiology
Genetics and Genomics
Immunology
CLINICAL
VEXAS Syndrome Can Cause Symptoms in the Eyes
A physician should be aware of the ophthalmological effects of autoinflammatory diseases, particularly this new entity called the VEXAS syndrome.
Autoimmunity
Clinical Research
Computational Biology
Epidemiology
Genetics and Genomics
Immunology
TRANSLATIONAL
Proteins Found in Urine Might Provide a Better Understanding of Juvenile Dermatomyositis
The study reports the use of urine as a biomarker source for JDM.
Autoimmunity
Clinical Research
Computational Biology
Immunology
Muscle Biology
CLINICAL
The Microbiomes of People with Recombination-Activating Gene (RAG) Deficiency Have Distinct Features, Including Antimicrobial Resistance Signatures
The study characterizes the colonization of eukaryotic RNA viruses in RAG-deficient patient population and also demonstrates the importance of these patients as potential reservoirs of viral persistence and evolution.
Clinical Research
Computational Biology
Genetics and Genomics
Microbiology and Infectious Diseases
Skin Biology
CLINICAL
Early Treatment Helps Reduce Long-Term Complications in Children with Job’s Syndrome
Early diagnosis and interventions have improved the quality of life for STAT3DN patients.
Clinical Research
Computational Biology
Genetics and Genomics
Microbiology and Infectious Diseases
Skin Biology
CLINICAL
Early-Onset Rash in Children with APECED Syndrome Accelerates Diagnosis
The modified clinical algorithm allows for faster diagnosis and treatment of children with APECED syndrome.
Clinical Research
Computational Biology
Genetics and Genomics
Microbiology and Infectious Diseases
Skin Biology
CLINICAL
Family-based Analysis of Whole Genomes in Lupus
The study identifies several novel SLE susceptibility genes in an ancestrally diverse childhood-onset lupus cohort.
Epidemiology
Genetics and Genomics
Health Disparities
BASIC
Role of Neurotrophin Receptor CD271 in Cutaneous Squamous Cell Carcinoma Invasiveness Identified
CD271 could be a promising pharmaceutical target for the treatment of cutaneous squamous cell carcinoma.
Cancer Biology
Developmental Biology
Genetics and Genomics
Molecular Biology and Biochemistry
Skin Biology
BASIC
Upregulation of the Protein Amphiregulin Protects Against Pressure Ulcers
Recombinant amphiregulin could be a potential therapeutic agent for cutaneous I/R injury.
Cancer Biology
Developmental Biology
Genetics and Genomics
Molecular Biology and Biochemistry
Skin Biology
BASIC
Macrophages Control Skin Susceptibility to a Common Bacterial Infection
Hypodermal macrophages play an important role in infection outcomes in the skin.
Clinical Research
Computational Biology
Microbiology and Infectious Diseases
Skin Biology
Virology
CLINICAL
Genetic Variants of PLCG2 Cause Immune Dysregulation Through Either Increased or Decreased Function
The study reports genotypic and phenotypic associations with functional variation in PLCG2.
Autoimmunity
Genetics and Genomics
NIAMS Remembers Scientist Emeritus Paul Plotz, M.D.
https://www.niams.nih.gov/newsroom/announcements/niams-remembers-scientist-emeritus-paul-plotz-md
NIAMS is saddened to share the news that Paul Plotz, M.D., who dedicated nearly four decades of service to science at the NIH, passed away on January 13, 2024, at the age of 86 after a long illness. Dr. Plotz was a world-renowned rheumatologist, immunologist, and researcher known internationally as an expert in myositis, an inflammatory muscle disease and rare autoimmune condition. He retired from NIH in 2011 after serving in a variety of leadership roles, including as chief of the NIAMS Arthritis and Rheumatism Branch, as well as acting scientific director and acting deputy director. He also was senior