Electron micrograph shows evidence of neutrophil extracellular trap (NET) formation in skin isolated from a patient with Stevens-Johnson syndrome (SJS) one day after onset.
Science Translational Medicine. 30 June 2021, Vol 13, Issue 600.
New research published in the journal Science Translational Medicine uncovers how neutrophils contribute to disease pathophysiology of Stevens-Johnson syndrome and toxic epidermal necrolysis, which are life-threatening mucocutaneous adverse drug reactions. An electron micrograph from this research (pictured) was selected as the cover image for the issue.
Read the abstract on PubMed:
Neutrophils initiate and exacerbate Stevens-Johnson syndrome and toxic epidermal necrolysis
Drs. Manao Kinoshita and Chris (Keisuke) Nagao, of the NIAMS Cutaneous Leukocyte Biology Section were key contributors on this study.