Overview

This program consists of several components: epidermal repair and regeneration, melanocyte biology, skin appendages, and vascular/lymphatics networks of the skin. Basic, translational, and clinical studies in these areas of research and support by this program. Within each of these components, specific focus areas include:

Skin Repair and Regeneration:

  • Basic studies of skin regeneration
  • Analysis of keratinocyte behavior during the normal wound healing process
  • New animal models of wound repair and regeneration
  • Basic, translational and clinical studies of chronic wounds
  • Abnormal wound healing in hereditary skin diseases
  • Skin scarring
  • Epithelial, mesenchymal and induced pluripotent stem cells in skin repair
  • Skin tissues engineering and improved skin equivalents

Melanocyte Biology:

  • Normal melanocyte development, differentiation and homeostasis
  • Skin pigmentation process and its regulation
  • Skin pigmentation disorders including hyperpigmentation and albinism
  • Photobiology of the skin
  • Melanocyte stem cells and their regulation
  • Early melanocyte transofrmation, melanocytic nevi, and melanoma prevention

Skin Appendages:

  • Development and maintenance of skin appendages
  • Diseases of skin appendages including hair, nails, sweat and sebaceous glands
  • Identifying potential stem cells and their niches
  • Function and regulation of stem cells in normal skin and diseases
  • Regenerative potential and conditions of skin appendages

Skin Vasculature and Lymphatic System:

  • Mechanisms of skin blood vessels and angiogenesis and lymphangiogenesis
  • Structure-function of blood and lymphatic vessels in normal skin development
  • Cellular, molecular biology and genetics of skin vasculature and lymphatics
  • Skin vascular malformations such as hemangioma and port wine stain

 

Funding Opportunities

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Research news

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The Division of Skin and Rheumatic Diseases promotes and supports basic, translational and clinical studies of skin, wound healing, and skin disorders, as well as adult and pediatric rheumatic diseases.

 

See all Scientific Areas in the Division of Skin and Rheumatic Diseases

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Contact Us

Alexey Belkin, Ph.D.

Program Director
6701 Democracy Blvd
Building: Democracy I, Suite 800
Bethesda MD 20892
Last Updated: August 2019