Dr. Dizon received his M.D./Ph.D. at the University of Alabama at Birmingham. His thesis project focused on understanding the functions of naturally-occurring self-reactive B cells and antibodies in murine models of autoimmune diabetes. He then completed an Internal Medicine-Pediatrics residency at the University of Rochester.
Pursuing his scientific interest in understanding the contributions of B cells and antibodies to the pathogenesis of systemic autoimmune diseases across the spectrum of life, Dr. Dizon then completed a combined rheumatology fellowship at NIAMS and Children’s National Hospital. He is currently a NIAMS Metzger Scholar in Translational Research continuing his training to become an independent physician-scientist.
Working in the lab of Dr. Susan Pierce, Dr. Dizon's research focuses on understanding the functions and regulation of autoreactive B cells in chronic infections (malaria), systemic autoimmunity (lupus), and long-lived immune responses elicited by vaccines (HPV vaccine). Autoreactive B cells are a component of the healthy immune system but are tightly regulated by a programmed state of hyporesponsiveness called anergy.
His research aims to understand how anergic B cells are activated or "awakened" under certain conditions to participate in responses to pathogens and vaccines, but also how these B cells function abnormally in systemic autoimmune diseases such as lupus.