Osteoarthritis Initiative

Updated February 23, 2015

The Osteoarthritis Initiative (OAI) is a multicenter, longitudinal, prospective observational study of knee osteoarthritis (OA). This Initiative is a public-private partnership between the National Institutes of Health (NIH) and private industry that seeks to improve diagnosis and monitoring of osteoarthritis (OA) and foster development of new treatments. The overall aim of the OAI is to develop a public-domain research resource to facilitate the scientific evaluation of biomarkers for osteoarthritis as potential surrogate endpoints for disease onset and progression. For more details and the most recent information on the study, please see the "Osteoarthritis Initiative Updated Summary."

News and Press Releases

Announcement February 20, 2015: 84-month Data from the Osteoarthritis Initiative Available

Announcement January 7, 2013: Availability of 60-month images and clinical data from the OAI

Announcement June 24, 2010: Availability of Central Image Assessments of OAI MR Images

Announcement June 15, 2010: Awards of Ancillary and Complementary Research to the Osteoarthritis Initiative

Announcement March 8, 2010: Availability of 36-month images and clinical data from the OAI

Announcement January 13, 2009: Osteoarthritis Initiative Biospecimen Availability

Announcement September 13, 2007: OAI Announces Availability of New Data and Images

Press Release August 1, 2006: Osteoarthritis Initiative Releases First Data

Press Release March 17, 2004: Enrollment Begins for Osteoarthritis Initiative

Press Release August 13, 2002: Sites Chosen for Public-Private Osteoarthritis Initiative

Press Release Public-Private Consortium Launches Osteoarthritis Initiative, July 17, 2001



Recent Meeting and Activities

OAI Biospecimens

Historical Items

Ancillary and Complementary Research to the Osteoarthritis Initiative

OAI Evaluation Meeting

June 2, 2008

OA Risk Factor Meeting

October 3, 2008

OA Initiative Prospectus

February 28-29, 2000 Meeting