¿Qué es la epidermólisis ampollosa? La epidermólisis ampollosa es un conjunto de enfermedades poco frecuentes que ocasionan fragilidad en la piel, por lo que esta se ampolla o se rasga. Esas rasgaduras, llagas y ampollas ocurren debido a una fricción o un golpe en la piel y pueden aparecer en cualquier parte del cuerpo. En casos graves, también pueden aparecer ampollas dentro del cuerpo. Generalmente, los síntomas de la enfermedad comienzan al nacer o durante la infancia y varían de leves a graves.
¿Qué es la alopecia areata? La alopecia areata es una enfermedad que provoca la caída del pelo. En la alopecia areata, el sistema inmunitario ataca los folículos pilosos (las estructuras de la piel que forman el pelo). Por lo general, la alopecia areata afecta la cabeza y la cara, aunque se puede perder el pelo en cualquier parte del cuerpo. En la mayoría de los casos, el pelo se cae en parches pequeños y redondos del tamaño de una moneda estadounidense de 25 centavos. En algunos casos, la caída del pelo es más extensa.
What is acne? Acne is a common skin condition that happens when hair follicles under the skin become clogged. Oil and dead skin cells plug the pores, and outbreaks of lesions (often called pimples or zits) can happen. Most often, the outbreaks occur on the face but can also appear on the back, chest, and shoulders. For most people, acne tends to go away by the time they reach their thirties, but some people in their forties and fifties continue to have this skin problem.
Led by Dr. Maria I. Morasso, the lab studies processes of epidermal differentiation, skin barrier formation and wound healing.
Led by Dr. Timothy Bhattacharyya, the unit investigates orthopedic conditions, including femur fractures and hip infections, and related treatments.
What is alopecia areata? Alopecia areata is a disease that causes hair loss. In alopecia areata, the immune system attacks the structures in skin that form hair (hair follicles). Alopecia areata usually affects the head and face, though hair can be lost from any part of the body. Hair typically falls out in small, round patches about the size of a quarter. In some cases, hair loss is more extensive.
Edward Cowen, M.D., leads the NIH Dermatology Consultation Service and oversees the Branch continuing medical education and resident education programs.
The Dermatology Branch conducts both clinical and basic research studying the etiology, diagnosis, and treatment of inflammatory and malignant diseases involving the skin and the host's response to these diseases.
Dr. Nagao’s research focuses on cellular and molecular mechanisms that regulate immunological and structural homeostasis in the skin.
What is spinal stenosis? Spinal stenosis happens when the spaces in the spine narrow and create pressure on the spinal cord and nerve roots. The spinal cord is a bundle of nerves that comes out of the base of the brain and runs down the center of the spine. The nerve roots branch out from the cord. In spinal stenosis, the narrowing usually occurs over time.
What is epidermolysis bullosa? Epidermolysis bullosa is a group of rare diseases that cause fragile skin that leads to blisters and tearing. Tears, sores, and blisters in the skin happen when something rubs or bumps the skin. They can appear anywhere on the body. In severe cases, blisters may also develop inside the body. The symptoms of the disease usually begin at birth or during infancy and range from mild to severe.
What is scleroderma? Scleroderma is an autoimmune connective tissue and rheumatic disease that causes inflammation in the skin and other areas of the body. This inflammation leads to patches of tight, hard skin. Scleroderma involves many systems in your body. A connective tissue disease is one that affects tissues such as skin, tendons, and cartilage. There are two major types of scleroderma: Localized scleroderma only affects the skin and the structures directly under the skin. Systemic scleroderma, also called systemic sclerosis, affects many systems in the body. This is the more serious type of scleroderma and can damage your blood
What is hidradenitis suppurativa? Hidradenitis suppurativa is a skin disease that causes pimple-like bumps or boils on and under the skin. The disease is chronic (long lasting) and can be painful. HS does not spread from one person to another. HS starts in the hair follicle in the skin and happens where areas of skin may touch or rub together. Poor personal hygiene habits, such as not bathing or shampooing your hair, do not cause HS. In most cases, the cause of the disease is unknown.
The FDA approved Olumiant (baricitinib) oral tablets to treat adult patients with severe alopecia areata. The action marks the first FDA approval of a systemic treatment (i.e. treats the entire body rather than a specific location) for alopecia areata.
Led by Dr. Vittorio Sartorelli, the lab studies mechanisms that regulate specification, differentiation, and regeneration of skeletal muscle cells.
Discussing Bone, Muscle, Skin, & Autoimmune Diseases: Info for American Indians, Alaska Natives - audio
A conversation between Dr. David R. Wilson, director of the NIH Tribal Health Research Office, and Dr. Lindsey A. Criswell, director of NIAMS, about information and resources for American Indians and Alaska Natives related to bone, muscle, skin, and autoimmune diseases.