골관절염이란 무엇인가요? 골관절염은 관절 내의 조직이 시간이 지나면서 손상될 때 생기는 관절 질환입니다. 골관절염은 가장 흔한 형태의 관절염이며 노년층에 더 흔합니다. 관절염이 있는 사람들은 보통 관절 통증이 있으며, 휴식 후에 잠시 동안 뻣뻣함(쉽게 움직일 수 없는 상태)을 느낍니다. 가장 흔히 골관절염이 생기는 관절은 다음과 같습니다. (손가락의 끝 부분과, 엄지의 맨 아래 부분과 끝 부분) 무릎. 고관절. 목. 허리 하부. 골관절염은 사람마다 다르게 영향을 미칩니다. 어떤 사람들은 일상 활동에 골관절염의 영향을 받지 않습니다. 어떤 사람들에게는, 골관절염이 심한 통증과 장애의 원인이 됩니다.
류마티스 관절염은 무엇인가요? 류마티스 관절염은 손목, 손, 발, 무릎, 척추 그리고 턱 등 관절에 주로 영향을 미치는 만성(지속성) 질환입니다. 류마티스 관절염은 다음과 같은 증상으로 이어지는 염증을 관절에 일으킵니다. 통증. 부기. 뻣뻣함. 기능 상실. 류마티스 관절염은 면역체계가 건강한 관절 조직을 공격하기 때문에 자가면역질환입니다. 보통, 면역체계는 감염과 질환으로부터 인체를 보호하는 데 도움을 줍니다. 류마티스 관절염은 평소와 달리 피로감을 느끼고, 이따금 열이 나며, 식욕을 상실하는 원인이 될 수 있습니다. 또한 심장, 폐, 혈액, 신경, 눈 그리고 피부에 다른 의학적 문제를 일으킬 수 있습니다. 치료를 통해 이 질환을 가진 사람들은 생산적인 생활을 영위하는 데 도움을 받을 수 있습니다.
This public-private partnership seeks to develop new ways of identifying and validating promising biological targets for diagnostics and drug development.
What is psoriatic arthritis? Psoriatic arthritis is a condition that causes swelling and pain in joints and the places where tendons and ligaments attach to bones. Most people who develop psoriatic arthritis already have psoriasis (a skin disease), but a small number have joint pain before the skin rash.
What is osteoarthritis? Osteoarthritis is a joint disease that happens when the tissues in the joint break down over time. It is the most common type of arthritis and is more common in older people. People with osteoarthritis usually have joint pain and, after rest, stiffness (inability to move easily) for a short period of time. The most commonly affected joints include the: Hands (ends of the fingers and at the base and ends of the thumbs). Knees. Hips. Neck. Lower back. Osteoarthritis affects each person differently. For some people, osteoarthritis does not affect day-to-day activities. For others, it causes
What is osteogenesis imperfecta? Osteogenesis imperfecta (OI) is a disease that causes your bones to break (fracture) easily. OI is also called brittle bone disease. Your symptoms may be mild or severe, depending on the type of OI you have.
What is osteonecrosis? Your bones are made up of living cells that need a blood supply to stay healthy. In osteonecrosis, blood flow to part of a bone is reduced. This causes death of bone tissue, and the bone can eventually break down and the joint will collapse. Osteonecrosis can happen to any bone, but most often it develops in the ends of long bones, such as the: Thigh bone. Upper arm bone. Less often, the bones of the elbows, ankles, feet, wrists, and hands are affected. When the disease involves part of a bone in a joint, it can
Research supported by the Accelerating Medicines Partnership (AMP) on Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) provides new insights into tissue damage for these autoimmune conditions. Findings include the identification of novel molecular signatures related to immune system signaling in kidney cells that may reflect their active role in disease process; molecular targets, including specific white blood cells, for potential treatment in lupus nephritis; and specific types of fibroblasts and white blood cells that are involved in rheumatoid arthritis.
What is rheumatoid arthritis? Rheumatoid arthritis (RA) is a chronic (long-lasting) disease that mostly affects joints, such as the wrist, hands, feet, spine, knees, and jaw. In joints, RA causes inflammation that leads to: Pain. Swelling Stiffness. Loss of function. Rheumatoid arthritis is an autoimmune disorder because the immune system attacks the healthy joint tissues. Normally, the immune system helps protect the body from infection and disease. RA may cause you to feel unusually tired, to have occasional fevers, and to have a loss of appetite. It also may cause other medical problems in the heart, lungs, blood, nerves, eyes
NIBIB-funded researchers are developing an implantable, biodegradable film that helps to regenerate the native cartilage at the site of damage. Their study, performed in rabbits, could be an initial, important step in the establishment of a new treatment for this common condition, osteoarthritis.
Led by Dr. Mariana Kaplan, the branch studies autoimmune diseases, like lupus and rheumatoid arthritis, seeking treatments and improved outcomes.
Background The Health Disparities in Osteoarthritis (OA) workshop brought together OA investigators with others who have expertise in health disparities to exchange ideas regarding how/why disparities in OA treatment and care exist and how they can be addressed. Panelists and speakers highlighted mechanisms through which behavioral and biomedical science integration can lead to better health in OA. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institute on Aging (NIA), and National Institute on Minority Health and Health Disparities (NIMHD) sponsored the workshop. It was organized by NIH staff and meeting co-chairs Drs. Arleen F. Brown (University