What is systemic lupus erythematosus (lupus)? Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body, including the: Skin. Joints. Heart. Lungs. Kidneys. Brain. Lupus happens when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation and, in some cases, permanent tissue damage. If you have lupus, you may have times of illness (flares) and times of wellness (remission). Lupus flares can be mild to serious, and they do not follow a pattern. However, with treatment, many people with lupus
¿Qué es el lupus eritematoso sistémico (lupus)? El lupus eritematoso sistémico es una enfermedad autoinmunitaria crónica (de larga duración) y que puede afectar muchas partes del cuerpo, tales como: la piel las articulaciones el corazón los pulmones los riñones el cerebro. El lupus ocurre cuando el sistema inmunitario, que normalmente ayuda a proteger al cuerpo contra infecciones y enfermedades, ataca sus propios tejidos. Este ataque causa inflamación y, en algunos casos, daño permanente de los tejidos. Si usted tiene lupus, puede haber momentos en los que está enfermo (brotes) y períodos en que está bien (remisión). Los brotes de lupus
What is pemphigus? Pemphigus is a type of disease where the body’s immune system attacks healthy cells in the top layer of skin (epidermis). It causes blisters on the skin and in the mouth, nose, throat, eyes, and genitals. Some forms of pemphigus can cause death if not treated.
What is joint replacement surgery? Joint replacement surgery removes damaged or diseased parts of a joint and replaces them with new, man-made parts. Replacing a joint can reduce pain and help you move and feel better. Hips and knees are replaced most often. Other joints that can be replaced include the shoulders, fingers, ankles, and elbows.
What is epidermolysis bullosa? Epidermolysis bullosa is a group of rare diseases that cause fragile skin that leads to blisters and tearing. Tears, sores, and blisters in the skin happen when something rubs or bumps the skin. They can appear anywhere on the body. In severe cases, blisters may also develop inside the body. The symptoms of the disease usually begin at birth or during infancy and range from mild to severe.
Two new studies funded in part by NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) describe efforts to develop stem cell-based approaches for treating Epidermolysis Bullosa (EB), a rare, genetic skin disease. The findings, which were published jointly in the journal, Science Translational Medicine, may lead to individualized therapies for EB, and possibly other genetic diseases. People with EB have skin that is so fragile that the slightest friction causes blisters. The severity of the disease ranges from limited tearing of skin on the hands and feet to widespread blistering and scarring, including mucosal surfaces like the
Lupus Ban Đỏ Hệ Thống (lupus) là gì? Lupus ban đỏ hệ thống (lupus) là một bệnh tự miễn mạn tính (kéo dài) có thể ảnh hưởng đến nhiều bộ phận của cơ thể, bao gồm: Da. Khớp. Tim. Phổi. Thận. Não. Lupus xảy ra khi hệ miễn dịch, mà thường giúp bảo vệ cơ thể khỏi nhiễm trùng và bệnh tật, tấn công các mô của chính mình. Cuộc tấn công này gây viêm và dẫn đến tổn thương mô vĩnh viễn trong một số trường hợp. Nếu quý vị mắc bệnh lupus, quý vị có thể có khoảng
A bioengineered molecule designed to bind together key components found in the fluid that surrounds joint areas may improve lubrication and minimize friction. This could potentially slow the degeneration of cartilage tissue that occurs in knee osteoarthritis, according to a study conducted in rats and funded in part by the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases. The study was published in Nature Materials. The synovial fluid that bathes our joints is composed of several types of lubricants, including hyaluronic acid (HA) and lubricin. In healthy joints, this fluid ensures that tissues move together smoothly and without
Using magnetic resonance imaging (MRI), a team of scientists has detected structural changes in the knee joint that precede signs of osteoarthritis seen on X-rays. The study, which was supported in part by the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), calls into question the assumption that damage to cartilage is the primary underlying cause of osteoarthritis. The findings appeared in the journal Arthritis and Rheumatology.
The AMP RA/SLE Program brings together the NIH and medical community to address rheumatoid arthritis and lupus with diagnostic and drug advancements.