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건강 토픽: 전신 홍반성 루푸스(루푸스) (Systemic Lupus Erythematosus)

https://www.niams.nih.gov/health-topics/lupus

전신 홍반성 루푸스(루푸스)란 무엇인가요? 전신 홍반성 루푸스(루푸스)는 다음과 같은 부위를 포함하여 몸의 여러 부분을 침범할 수 있는 만성(지속성) 자가면역 질환입니다. 피부. 관절. 심장. 폐. 신장. 뇌. 루푸스는 감염과 질환으로부터 몸을 보호하는 데 도움이 되는 면역체계가 자신의 조직을 공격할 때 일어납니다. 경우에 따라서, 이 공격은 염증과 영구적인 조직 손상을 일으킵니다. 루푸스가 있는 경우에는 아플 때(발적)와 건강한 때(증상 소멸)가 있을 수 있습니다. 루푸스 발적은 경증에서 중증까지 있을 수 있으며 패턴을 따르지 않습니다. 그러나 루푸스를 가진 많은 사람들이 치료를 통해 이 질환을 관리할 수 있습니다.

Ichthyosis

https://www.niams.nih.gov/health-topics/ichthyosis

What is ichthyosis? Ichthyosis is a group of skin disorders. It leads to dry, itchy skin that appears scaly, rough, and red. The symptoms can range from mild to severe. Ichthyosis can affect only the skin, but sometimes the disease can affect internal organs, too.

Systemic Lupus Erythematosus (Lupus)

https://www.niams.nih.gov/health-topics/lupus

What is systemic lupus erythematosus (lupus)? Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body, including the: Skin. Joints. Heart. Lungs. Kidneys. Brain. Lupus happens when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation and, in some cases, permanent tissue damage. If you have lupus, you may have times of illness (flares) and times of wellness (remission). Lupus flares can be mild to serious, and they do not follow a pattern. However, with treatment, many people with lupus

Fibromyalgia

https://www.niams.nih.gov/health-topics/fibromyalgia

What is fibromyalgia? Fibromyalgia is a long-lasting disorder that causes pain and tenderness throughout the body. It also can cause you to feel overly tired (fatigue) and have trouble sleeping. Doctors do not fully understand what causes fibromyalgia, but people with the disorder are more sensitive to pain.

New clues on tissue damage identified in rheumatoid arthritis and lupus

https://www.niams.nih.gov/newsroom/press-releases/new-clues-tissue-damage-identified-rheumatoid-arthritis-and-lupus

Research supported by the Accelerating Medicines Partnership (AMP) on Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) provides new insights into tissue damage for these autoimmune conditions. Findings include the identification of novel molecular signatures related to immune system signaling in kidney cells that may reflect their active role in disease process; molecular targets, including specific white blood cells, for potential treatment in lupus nephritis; and specific types of fibroblasts and white blood cells that are involved in rheumatoid arthritis.

Casting the NET Wide: How Neutrophils Shape Chronic Autoimmune and Inflammatory Diseases

https://www.niams.nih.gov/casting-net-wide-how-neutrophils-shape-chronic-autoimmune-and-inflammatory-diseases

Known as the “disease with a thousand faces,” systemic lupus erythematosus is a lifelong autoimmune disease with a wide range of symptoms and signs—fatigue, fever, joint pain, facial rash and skin lesions, shortness of breath, and more. It may develop suddenly or slowly and be mild or severe, with people affected going through periods of flare up and remission of their symptoms.