What is systemic lupus erythematosus (lupus)? Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body, including the: Skin. Joints. Heart. Lungs. Kidneys. Brain. Lupus happens when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation and, in some cases, permanent tissue damage. If you have lupus, you may have times of illness (flares) and times of wellness (remission). Lupus flares can be mild to serious, and they do not follow a pattern. However, with treatment, many people with lupus
¿Qué es el lupus eritematoso sistémico (lupus)? El lupus eritematoso sistémico es una enfermedad autoinmunitaria crónica (de larga duración) y que puede afectar muchas partes del cuerpo, tales como: la piel las articulaciones el corazón los pulmones los riñones el cerebro. El lupus ocurre cuando el sistema inmunitario, que normalmente ayuda a proteger al cuerpo contra infecciones y enfermedades, ataca sus propios tejidos. Este ataque causa inflamación y, en algunos casos, daño permanente de los tejidos. Si usted tiene lupus, puede haber momentos en los que está enfermo (brotes) y períodos en que está bien (remisión). Los brotes de lupus
What are autoinflammatory diseases? Autoinflammatory diseases refer to problems with the immune system, which usually fights off viruses, bacteria, and infection. The problem causes your immune cells to attack your body by mistake. This can cause swelling that produces fever, rash, joint swelling, or serious buildup of a blood protein in your organs.
What is rosacea? Rosacea (ro-ZAY-she-ah) is a long-term disease that causes reddened skin and pimples, usually on the face. It can also make skin thicker and cause eye problems.
What are shoulder problems? Most shoulder problems happen when soft tissues in the joint and shoulder region break down.
What is fibromyalgia? Fibromyalgia is a long-lasting or chronic disorder that causes muscle pain and fatigue (feeling tired). If you have fibromyalgia, you have pain and tenderness throughout your body. Sometimes you may have two or more chronic pain conditions at the same time, such as: Chronic fatigue syndrome. Endometriosis. Irritable bowel syndrome. Interstitial cystitis. Temporomandibular joint dysfunction (TMJ). Vulvodynia.
Lupus Ban Đỏ Hệ Thống (lupus) là gì? Lupus ban đỏ hệ thống (lupus) là một bệnh tự miễn mạn tính (kéo dài) có thể ảnh hưởng đến nhiều bộ phận của cơ thể, bao gồm: Da. Khớp. Tim. Phổi. Thận. Não. Lupus xảy ra khi hệ miễn dịch, mà thường giúp bảo vệ cơ thể khỏi nhiễm trùng và bệnh tật, tấn công các mô của chính mình. Cuộc tấn công này gây viêm và dẫn đến tổn thương mô vĩnh viễn trong một số trường hợp. Nếu quý vị mắc bệnh lupus, quý vị có thể có khoảng
What are heritable disorders of connective tissue? There are more than 200 heritable disorders of connective tissue that can affect the tissues between the cells of your body that give tissues form and strength. All of these diseases are directly related to problems in genes that are responsible for building connective tissues. The disorders are called “heritable,” because they are passed on from parent to child. Some heritable disorders of connective tissue change the look and growth of skin, bones, joints, heart, blood vessels, lungs, eyes, and ears. Others change how these tissues work. Many, but not all, are rare
The AMP RA/SLE Program brings together the NIH and medical community to address rheumatoid arthritis and lupus with diagnostic and drug advancements.
Same Immune Regulatory Protein Found to Play Instrumental Role in Two Hereditary Autoinflammatory Diseases
Research funded in part by the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has revealed a new role for A20, a protein that regulates a key immune response pathway, in certain early-onset autoinflammatory diseases. The results suggest that targeting this pathway could be an effective strategy for treating these diseases, and possibly related conditions, as well.