What is systemic lupus erythematosus (lupus)? Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body, including the: Skin. Joints. Heart. Lungs. Kidneys. Brain. Lupus happens when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation and, in some cases, permanent tissue damage. If you have lupus, you may have times of illness (flares) and times of wellness (remission). Lupus flares can be mild to serious, and they do not follow a pattern. However, with treatment, many people with lupus
¿Qué es el lupus eritematoso sistémico (lupus)? El lupus eritematoso sistémico es una enfermedad autoinmunitaria crónica (de larga duración) y que puede afectar muchas partes del cuerpo, tales como: la piel las articulaciones el corazón los pulmones los riñones el cerebro. El lupus ocurre cuando el sistema inmunitario, que normalmente ayuda a proteger al cuerpo contra infecciones y enfermedades, ataca sus propios tejidos. Este ataque causa inflamación y, en algunos casos, daño permanente de los tejidos. Si usted tiene lupus, puede haber momentos en los que está enfermo (brotes) y períodos en que está bien (remisión). Los brotes de lupus
What are autoinflammatory diseases? Autoinflammatory diseases refer to problems with the immune system, which usually fights off viruses, bacteria, and infection. The problem causes your immune cells to attack your body by mistake. This can cause swelling that produces fever, rash, joint swelling, or serious buildup of a blood protein in your organs.
Is your back hurting? You’re in good company. In any 3-month period, about 1 in 4 adults in the U.S. has at least one day of back pain, mostly in the lower back. The back is a complicated structure. Its center is the spine, which is made up of 33 bones called vertebrae, stacked in a column. The nerves of the spinal cord run in a tunnel through the middle of those bones. Spongy discs between the vertebrae act as cushions. Ligaments and tendons hold everything together. A lot of things can go wrong with your back. A strained muscle
What is osteonecrosis? Osteonecrosis is a bone disease. It results from the loss of blood supply to the bone. Without blood, the bone tissue dies. This causes the bone to collapse. It may also cause the joints that surround the bone to collapse. If you have osteonecrosis, you may have pain or be limited in your physical activity. Osteonecrosis can develop in any bone, most often in the: Thigh bone (femur). Upper arm bone (humerus). Knees. Shoulders. Ankles. It is also called: Avascular necrosis. Aseptic necrosis. Ischemic necrosis.
What is back pain? Back pain is one of the most common medical problems in the United States. It might feel like a dull, constant ache or a sudden, sharp pain. Back pain can result from: An accident. A fall. Lifting something heavy. Changes that happen in the spine as you age. A disorder or medical condition. Treatment depends on the cause and symptoms of your pain. You can do things to improve your health and lower your chance of developing chronic (long-lasting) back pain.
Lupus Ban Đỏ Hệ Thống (lupus) là gì? Lupus ban đỏ hệ thống (lupus) là một bệnh tự miễn mạn tính (kéo dài) có thể ảnh hưởng đến nhiều bộ phận của cơ thể, bao gồm: Da. Khớp. Tim. Phổi. Thận. Não. Lupus xảy ra khi hệ miễn dịch, mà thường giúp bảo vệ cơ thể khỏi nhiễm trùng và bệnh tật, tấn công các mô của chính mình. Cuộc tấn công này gây viêm và dẫn đến tổn thương mô vĩnh viễn trong một số trường hợp. Nếu quý vị mắc bệnh lupus, quý vị có thể có khoảng
Same Immune Regulatory Protein Found to Play Instrumental Role in Two Hereditary Autoinflammatory Diseases
Research funded in part by the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has revealed a new role for A20, a protein that regulates a key immune response pathway, in certain early-onset autoinflammatory diseases. The results suggest that targeting this pathway could be an effective strategy for treating these diseases, and possibly related conditions, as well.
The AMP RA/SLE Program brings together the NIH and medical community to address rheumatoid arthritis and lupus with diagnostic and drug advancements.