What is systemic lupus erythematosus (lupus)? Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body, including the: Skin. Joints. Heart. Lungs. Kidneys. Brain. Lupus happens when the immune system, which normally helps protect the body from infection and disease, attacks its own tissues. This attack causes inflammation and, in some cases, permanent tissue damage. If you have lupus, you may have times of illness (flares) and times of wellness (remission). Lupus flares can be mild to serious, and they do not follow a pattern. However, with treatment, many people with lupus
¿Qué es el lupus eritematoso sistémico (lupus)? El lupus eritematoso sistémico es una enfermedad autoinmunitaria crónica (de larga duración) y que puede afectar muchas partes del cuerpo, tales como: la piel las articulaciones el corazón los pulmones los riñones el cerebro. El lupus ocurre cuando el sistema inmunitario, que normalmente ayuda a proteger al cuerpo contra infecciones y enfermedades, ataca sus propios tejidos. Este ataque causa inflamación y, en algunos casos, daño permanente de los tejidos. Si usted tiene lupus, puede haber momentos en los que está enfermo (brotes) y períodos en que está bien (remisión). Los brotes de lupus
What is arthritis? "Arthritis" literally means joint inflammation. Although joint inflammation is a symptom or sign rather than a specific diagnosis, the term arthritis is often used to refer to any disorder that affects the joints. Joints are places where two bones meet, such as your elbow or knee. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, heart, or skin, can also be affected. Fortunately, current treatments allow most people with arthritis to lead active and productive lives.
What is Behçet’s disease? Behçet’s disease can affect different parts of your body. If you have the disease, you probably have sores in the mouth or on the genitals (sex organs). More serious symptoms can include swelling, heat, redness, and pain in the eyes and other parts of the body. The disease is named after the doctor who first described it, Dr. Hulusi Behçet.
What is gout? Gout is a type of arthritis that causes pain and swelling in your joints, usually as flares that last for a week or two, and then go away. Gout flares often begin in your big toe or a lower limb. Gout happens when high levels of a substance called serum urate build up in your body. When this happens, needle-shaped crystals form in and around the joint. This leads to inflammation and arthritis of the joint. However, many people with high levels of serum urate will not develop gout. With early diagnosis, treatment, and lifestyle changes, gout
Lupus Ban Đỏ Hệ Thống (lupus) là gì? Lupus ban đỏ hệ thống (lupus) là một bệnh tự miễn mạn tính (kéo dài) có thể ảnh hưởng đến nhiều bộ phận của cơ thể, bao gồm: Da. Khớp. Tim. Phổi. Thận. Não. Lupus xảy ra khi hệ miễn dịch, mà thường giúp bảo vệ cơ thể khỏi nhiễm trùng và bệnh tật, tấn công các mô của chính mình. Cuộc tấn công này gây viêm và dẫn đến tổn thương mô vĩnh viễn trong một số trường hợp. Nếu quý vị mắc bệnh lupus, quý vị có thể có khoảng
What are knee problems? Knee problems happen when you injure or develop disease in your knee and it can’t do its job. The knees provide stable support for the body. They also allow your legs to bend and straighten. Both flexibility and stability are needed to stand, walk, run, crouch, jump, and turn. Other parts of your body help the knees do their job. These are: Bones. Cartilage. Muscles. Ligaments. Tendons.
Same Immune Regulatory Protein Found to Play Instrumental Role in Two Hereditary Autoinflammatory Diseases
Research funded in part by the NIH’s National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) has revealed a new role for A20, a protein that regulates a key immune response pathway, in certain early-onset autoinflammatory diseases. The results suggest that targeting this pathway could be an effective strategy for treating these diseases, and possibly related conditions, as well.
The AMP RA/SLE Program brings together the NIH and medical community to address rheumatoid arthritis and lupus with diagnostic and drug advancements.