什麼是痤瘡？ 痤瘡是常見的皮膚狀況，是由皮膚下面的毛囊堵塞造成的。油脂和死亡的皮膚細胞堵住毛孔，可爆發皮膚病灶（通常稱為粉刺或青春痘）。爆發最常見於面部，但也可出現在背部、胸部和肩部。 大多數人的痤瘡通常會在三十多歲之前消失，但有些人到四十多歲和五十多歲時仍然還有這一皮膚問題
何謂異位性皮膚炎？ 異位性皮膚炎通常稱為濕疹。這是一種慢性（長期）疾病，造成皮膚炎症和刺激症狀，導致極度瘙癢。抓撓會引起： 發紅。 腫脹。 皸裂。 滲出透明液體。 結痂。 脫皮。 在大多數情況下，有時病情惡化（稱為急性發作），然後皮膚情況有所改善或症狀完全消失（稱為緩解）。 異位性皮膚炎是一種常見病症，任何人都可能患上。但異位性皮膚炎通常是在兒童期開始出現。異位性皮膚炎不會從一個人傳給另一個人。沒有人知道異位性皮膚炎的病因是什麼。根據症狀的嚴重程度，異位性皮膚炎患者的生活可能並不容易，但治療可幫助控制症狀。
What is acne? Acne is a common skin condition that happens when hair follicles under the skin become clogged. Oil and dead skin cells plug the pores, and outbreaks of lesions (often called pimples or zits) can happen. Most often, the outbreaks occur on the face but can also appear on the back, chest, and shoulders. For most people, acne tends to go away by the time they reach their thirties, but some people in their forties and fifties continue to have this skin problem.
What is Paget’s disease? Paget’s disease of bone is a chronic (long-lasting) disorder that causes bones to grow larger and become weaker than normal. Usually only one or a few bones have the disease. Many people with Paget’s disease do not have symptoms. However, the bone changes can cause: Bone pain. Misshapen bones. Broken bones (fractures). Problems in the joints near the bones with the disease. With treatment, many people can: Manage their symptoms. Improve pain. Control the effects of the disease.
What is atopic dermatitis? Atopic dermatitis, often called eczema, is a chronic (long-lasting) disease that causes the skin to become inflamed and irritated, making it extremely itchy. Scratching leads to: Redness. Swelling. Cracking. “Weeping” clear fluid. Crusting. Scaling. In most cases, there are times when the disease is worse, called flares, followed by times when the skin improves or clears up entirely, called remissions. Atopic dermatitis is a common condition, and anyone can get the disease. However, it usually begins in childhood. Atopic dermatitis cannot be spread from person to person. No one knows what causes atopic dermatitis. Depending on
What is osteonecrosis? Your bones are made up of living cells that need a blood supply to stay healthy. In osteonecrosis, blood flow to part of a bone is reduced. This causes death of bone tissue, and the bone can eventually break down and the joint will collapse. Osteonecrosis can happen to any bone, but most often it develops in the ends of long bones, such as the: Thigh bone. Upper arm bone. Less often, the bones of the elbows, ankles, feet, wrists, and hands are affected. When the disease involves part of a bone in a joint, it can
What are autoinflammatory diseases? Autoinflammatory diseases refer to problems with the immune system, which usually fights off viruses, bacteria, and infection. The problem causes your immune cells to attack your body by mistake. This can cause swelling that produces fever, rash, joint swelling, or serious buildup of a blood protein in your organs.
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A type of skin cell called a dermal fibroblast can make an antimicrobial compound called cathelicidin in response to infection by acne-causing bacteria.
Human skin is home to diverse ecosystems including bacteria, viruses, and fungi. These microbial communities comprise hundreds of species and are collectively known as the skin microbiome.
Researchers published a proof-of-principle paper in the journal Science Immunology demonstrating just how precision medicine for inflammatory skin rashes might work.
A treatment for severe skin inflammation that works well in lean mice made the condition worse in obese mice because of immune-cell changes associated with obesity.
Discussing Bone, Muscle, Skin, & Autoimmune Diseases: Info for American Indians, Alaska Natives - audio
A conversation between Dr. David R. Wilson, director of the NIH Tribal Health Research Office, and Dr. Lindsey A. Criswell, director of NIAMS, about information and resources for American Indians and Alaska Natives related to bone, muscle, skin, and autoimmune diseases.