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This image shows bone formation with blood vessels induced by a type of human stem cells (progenitor cells), as examined in a rodent spinal fusion model. Researchers altered progenitor cells so they made more of a protein known as WISP-1. This protein turns on genes that control bone formation. When the researchers injected the engineered human stem cells into a mouse model of spinal fusion surgery, they saw new bone formation and fusion.

Aaron W. James, M.D., Ph.D., Johns Hopkins Medicine
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Broad Area of Study