Biodata Mining and Discovery SectionLed by Dr. Hong-Wei Sun, the Biodata Mining and Discovery Section facilitates biomedical research to support NIAMS IRP scientists and their discoveries.
Clinical and Investigative Orthopedics Surgery UnitLed by Dr. Timothy Bhattacharyya, the unit investigates orthopedic conditions, including femur fractures and hip infections, and related treatments.
Clinical Research @ NIAMSBased on Translational Research methods, NIAMS clinical trials give researchers a biological understanding of a disease that can inform their studies.
Cutaneous Development and Carcinogenesis SectionLed by Dr. Isaac Brownell, the Cutaneous Development and Carcinogenesis Section studies the signaling pathways such as Hedgehog signaling that regulate the development and maintenance of normal skin and the changes in these signals that occur during the formation of skin cancer
Cutaneous Leukocyte Biology SectionLed by Keisuke (Chris) Nagao, the section investigates cellular and molecular mechanisms that regulate immunological and structural homeostasis in the skin.
Cutaneous Malignancies UnitThe Cutaneous Malignancies Unit investigates the mechanisms and processes underlying skin cancers such as Merkel cell carcinoma (MCC), acral lentiginous melanoma (ALM), and squamous cell carcinoma (SCC).
Cutaneous Microbiome and Inflammation SectionLed by Heidi Kong, the section uses genomics to study the skin microbes in healthy individuals and patients with skin diseases and to expand our understanding of host-microbe interactions.
Dermatology BranchThe Dermatology Branch conducts both clinical and basic research studying the etiology, diagnosis, and treatment of inflammatory and malignant diseases involving the skin and the host's response to these diseases.
Dermatology Consultation ServiceThe Dermatology Consultation Service at the NIH Clinical Center evaluates patients with a variety of rare diseases with cutaneous manifestations. In addition, patients who experience adverse reactions to experimental therapeutic agents or manifest unrelated skin conditions while at the NIH are evaluated and treated. Dermatology Branch clinical fellows, fellows from other NIH Institutes, and visiting dermatology residents from around the country receive training on the Dermatology consult service.
Flow Cytometry SectionThe Flow Cytometry Section provides state-of-the-art multi-parameter cellular analysis and cell sorting for NIAMS researchers and investigators.
Functional Immunogenomics SectionThe Functional Immunogenomics Unit applies cutting-edge genomic technologies to the solution of medically important questions related to the immune system. A major focus is on the molecular dissection of the immunoregulatory effects of glucocorticoids
Genomic Technology Section
The mission of the Genomic Technology Section is to help NIAMS investigators solve highly diverse biological and biomedical research questions by providing a diverse portfolio of sequencing services as well as consultation and training for researchers with specific needs or challenging problems. The core is a state-of-the-art laboratory facility equipped with the latest DNA sequencing and library preparation technologies.
Juvenile Myositis Pathogenesis and Therapeutics UnitLed by Dr. Hanna Kim, this unit studies juvenile myositis, including juvenile dermatomyositis, by comprehensively evaluating patients to better understand disease pathogenesis and conducting early phase clinical trials to evaluate new treatments.
Laboratory Animal Care and Use SectionLACU provides animal care services to support NIAMS Intramural Research Program Branches and Laboratories.
Laboratory of Molecular Immunogenetics, Genomics and Immunity SectionThe lab investigates immune cell processes, and how they impact autoimmune and other inflammatory diseases.
Laboratory of Muscle Stem Cells and Gene RegulationLed by Dr. Vittorio Sartorelli, the lab studies mechanisms that regulate specification, differentiation, and regeneration of skeletal muscle cells.
Laboratory of Skin BiologyLed by Dr. Maria I. Morasso, the lab studies processes of epidermal differentiation, skin barrier formation and wound healing.
Laboratory of Structural Cell BiologyLed by Dr. Naoko Mizuno, the Laboratory of Structural Cell Biology aims to understand the molecular mechanisms governing specialized cell shapes, such as those of neurons, activated immune cells or platelets and certain cancer cells.
Light Imaging SectionThe NIAMS Light Imaging Section provides scientists light imaging tools, and training on analysis of images with techniques of light microscopy.
Lupus Clinical Trials UnitLed by Dr. Sarfaraz Hasni, the unit studies the natural history and pathogenesis of lupus and involved in designing and conducting early phase clinical trials.
Lupus Genomics and Global Health Disparities UnitDr. Lewandowski leads a team of scientists studying systemic lupus erythematosus patients in populations around the globe. Her research focuses on genetic drivers of severe disease and inflammation in diverse cohorts worldwide.
Lymphocyte Signaling UnitLed by Dr. Tasha Morrison, the Lymphocyte Signaling Unit studies molecular processes that control immune cell development and function.
Lymphocyte Transcriptional Regulation UnitThe Transcriptional Regulation of Lymphocytes Unit focuses on the mechanisms behind T Cell specification. We integrate several next-generation sequencing techniques, such as RNAseq, to look at differential gene expression and ATACseq, to investigate T cell specification at both the transcriptional and epigenetic levels.
Molecular Immunology and Inflammation BranchLed by Dr. John O’Shea, the branch investigates how T cells play a role in both immune defense and development of immune-mediated diseases.
Muscle Disease SectionLed by Dr. Andrew Mammen, the unit researches human muscle diseases, as well the basic biology of skeletal muscle regeneration.
Muscle Energetics LaboratoryThe focus of Dr. Glancy’s muscle energetics research program is to determine how mitochondria are optimized within muscle cells to help maintain energy homeostasis during the large change in energy demand caused by muscle contraction.
Office of Science and Technology
The Office of Science and Technology (OST) is responsible for NIAMS Labs core facilities. It provides and develops new technologies, advises the Scientific Director, Lab and Branch Chiefs, and other key officials on science and technology. OST initiates collaborative, cooperative and service activities that facilitate the conduct of science and coordinates the core technological facilities of the Intramural Research Program.