Overview

This program supports research on bone biology, clinical research on osteoporosis, metabolic bone disorders and bone quality.

Bone biology & skeletal homeostasis studies include:

  • Osteoclasts, osteoblasts, and osteocytes in bone remodeling and mechanotransduction.
  • Signaling mechanisms mediating effects of hormones, growth factors, and cytokines in bone cells.
  • Bone matrix composition, structure, and function.
  • Pre-clinical development of novel therapeutics for osteoporosis.

Clinical studies in osteoporosis and metabolic bone disorders include:

  • Epidemiology, pathogenesis, and pathophysiology.
  • Environmental and genetic risk factors.
  • Treatment, prevention, and diagnosis.

Bone quality and skeletal imaging:

  • In vivo methods for macro and micro scale imaging of bone.
  • Architecture and mechanical properties of bone.
  • Multi-scale modeling of the human bone.
  • Assessment of bone quality.
  • Clinical studies related to bone strength and density.

Funding Opportunities

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About the Division

Contact Us

Kristy Nicks, Ph.D.

Program Director
6701 Democracy Boulevard
Building: Democracy 1, Room: 837
Bethesda MD 20892-4872
Last Updated: