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These FAQs apply to the following funding opportunity:

Are there any changes to the STAR funding opportunity from the last issue (PA-18-914)?

The STAR funding opportunity was previously issued as a Program Announcement but is now issued as a Notice of Special Interest (NOSI). You should submit your application using PA-20-272 (or subsequent re-issues of that PA) and include this NOSI (NOT-AR-22-003) in the Agency Routing Identifier Field (box 4B) of the SF424 R&R form. If applicants do not include this NOSI identifier number, the application will not be considered for a STAR award.

I received my first R01, am I eligible for the STAR award?

No, an eligible PI should successfully renew their first R01 as a Type 2 and currently be in the 2nd or 3rd year of the Type 2 R01 award. The PI must also have Early Stage Investigator (ESI) status (as defined here) at the time of the first R01 award.

What if I was a New Investigator (NI) when I received my first R01? Am I eligible for the STAR?

No, an eligible PI must have an ESI status at the time of his/her first R01 award.

If I have more than 2 R01s (or R01-equivalent) grants, can I be eligible?

No, PI should not have a history of receiving more than two R01-equivalent grants (e.g. if you received one R01, one R56, and one U01, you would be ineligible).

What is considered an R01-equivalent grant?

As defined in the NIH Glossary, R01-Equivalent Grants are defined as activity codes: DP1, DP2, DP5, R01, R23, R29, R37, R56, RF1, RL1, U01 and R35.

If my first R01 was awarded from a different NIH institute, am I eligible for the STAR award?

No, your first R01 must have been awarded by NIAMS.

My first R01 and/or Type 2 R01 awards are multi-PI (MPI) awards. Is that allowed?

Multiple PD/PI awards are not eligible for consideration for STAR award.

I received my first R01 as an ESI under a funding opportunity that does not allow renewals (e.g. PAR-21-053: Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases). What are my options if I want to be considered for the STAR Award?

If the funding opportunity from your first R01 does not allow renewals, you may submit your Type 2 R01 proposal to a different funding opportunity, as long as your proposal is in line with, or a continuation of, the first R01.

My project has vertebrate animal subjects and/or human subjects, do I still need to provide documentations with approvals?

Yes, although this is a supplement, the PI still needs to provide standard documents as if it were a regular grant. For instance, the STAR application should provide a Vertebrate Animal Section and an Institutional Animal Care and Use Committee (IACUC) approval for projects with animal subjects. For projects with human subjects, a Human Subjects section, an Institutional Review Board (IRB) approval and verification of human subjects education requirements should be provided.


Please contact the STAR coordinator at with any additional questions.

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Heiyoung Park, Ph.D.

Program Director
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Building: Democracy I, Suite 800
Bethesda MD 20892-4872

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Leslie Littlejohn

Grants Management Analyst
6701 Democracy Blvd
Building: Democracy I, Suite 800
Bethesda MD 20892-4872
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