96-month Images and Clinical Data from the Osteoarthritis Initiative Available via OAI Online

October 15, 2015 (historical)

The NIAMS announces that the University of California, San Francisco (UCSF) Coordinating Center for the Osteoarthritis Initiative (OAI) has released data from the 96-month follow-up visit of the OAI cohort, including questionnaire data. These data are available to registered users of OAI Online.

In addition, data from the 108-month follow-up interview are also available. To date, annual data from the baseline through the 108-month follow-up contact have been released for the entire cohort. In addition to annual data, semi-annual data from the 18-month and 30-month follow-up visits for a subset of participants have been released as well.

Moreover, the following datasets have been updated:

  • Outcomes database that includes endpoint data through the 108-month follow-up contact.
  • Measurement Inventory for Study Planning database. This database can be used to facilitate the planning of analyses using the central image assessments and/or OAI images.

Just a reminder that MR I and x-ray images from the baseline through the 96-month follow-up visit are available. Also available is the subset of images that were measured as part of the OA Biomarkers Consortium Foundation for the National Institutes of Health (FNIH) Project. Log onto the OAI Online website (https://oai.epi-ucsf.org/datarelease/ External Web Site Policy) to obtain the images. You will need to review and sign a Data Users Agreement, provide an email address, complete a request for research image set, and provide your own hard drive. (refer to the detailed specifications provided on OAI Online).

Biological specimens from the OAI are available by application. Biospecimens include serum, plasma, urine, DNA, and RNA (note: RNA would need to be extracted) from the entire OAI cohort for the baseline through the 72-month follow-up visits. Please refer to the OAI Online website for the Access Instructions and the Application Guide for Requesting Existing Biospecimens (https://oai.epi-ucsf.org/datarelease/ External Web Site Policy).

Always acknowledge the OAI in your publications. The OAI and its funding sources should be acknowledged in ALL publications that use data from the OAI public use datasets. Please refer to the OAI Guidelines for Publications Using Public Use Datasets (https://oai.epi-ucsf.org/datarelease/Docs/OAIPubsGuidePublicData.pdf).

Interest in the OAI remains high. To date, there are over 3,800 people, representing over 100 countries, who have registered for OAI Online and have downloaded almost 27,000 datasets.