Summary

Dr. Xiang Wang received her PhD in Biochemistry and Molecular Biology from Wuhan University. Her PhD research focused on epigenetic regulation in cell signaling pathways. She currently works in Dr. Casellas' lab and her interest is the organization of nuclear architecture.

Research Statement

Dr. Wang's research interests include nuclear architecture and epigenetic regulation.

Scientific Publications

TTLL12 Inhibits the Activation of Cellular Antiviral Signaling through Interaction with VISA/MAVS.

Ju LG, Zhu Y, Lei PJ, Yan D, Zhu K, Wang X, Li QL, Li XJ, Chen JW, Li LY, Wu M
Journal of immunology (Baltimore, Md. : 1950).
2017 Feb 1;
198(3).
doi: 10.4049/jimmunol.1601194
PMID: 28011935

SPOP-containing complex regulates SETD2 stability and H3K36me3-coupled alternative splicing.

Zhu K, Lei PJ, Ju LG, Wang X, Huang K, Yang B, Shao C, Zhu Y, Wei G, Fu XD, Li L, Wu M
Nucleic acids research.
2017 Jan 9;
45(1).
doi: 10.1093/nar/gkw814
PMID: 27614073

The EZH1-SUZ12 complex positively regulates the transcription of NF-κB target genes through interaction with UXT.

Su SK, Li CY, Lei PJ, Wang X, Zhao QY, Cai Y, Wang Z, Li L, Wu M
Journal of cell science.
2016 Jun 15;
129(12).
doi: 10.1242/jcs.185546
PMID: 27127229

WDR82 Negatively Regulates Cellular Antiviral Response by Mediating TRAF3 Polyubiquitination in Multiple Cell Lines.

Zhu K, Wang X, Ju LG, Zhu Y, Yao J, Wang Y, Wu M, Li LY
Journal of immunology (Baltimore, Md. : 1950).
2015 Dec 1;
195(11).
doi: 10.4049/jimmunol.1500339
PMID: 26519536

Histone H3K4 methyltransferase Mll1 regulates protein glycosylation and tunicamycin-induced apoptosis through transcriptional regulation.

Wang X, Ju L, Fan J, Zhu Y, Liu X, Zhu K, Wu M, Li L
Biochimica et biophysica acta.
2014 Nov;
1843(11).
doi: 10.1016/j.bbamcr.2014.06.013
PMID: 24983772

MLL1, a H3K4 methyltransferase, regulates the TNFα-stimulated activation of genes downstream of NF-κB.

Wang X, Zhu K, Li S, Liao Y, Du R, Zhang X, Shu HB, Guo AY, Li L, Wu M
Journal of cell science.
2012 Sep 1;
125(Pt 17).
doi: 10.1242/jcs.103531
PMID: 22623725

Education

2014 - PhD in Biochemistry and Molecular Biology, Wuhan University

Last Updated: June 2020