Dr. Vivek Thumbigere Math graduated with a Bachelor of Dental Surgery degree in 2003 from Sri Siddhartha Dental College, India. He then received a certificate in periodontology in 2011 and a Ph.D. in oral biology in 2013 from the University of Minnesota School of Dentistry. He came to the NIH in 2013 for postdoctoral training in the Laboratory of Oral and Connective Tissue Biology. Dr. Thumbigere Math is a diplomate of the American Board of Periodontology.

Research Statement

Dr. Vivek Thumbigere Math’s research focuses on studying the molecular biology of dental-oral-craniofacial development, with an emphasis on the periodontal complex. We aim to understand cells and signals influencing tooth, bone, and periodontal ligament development in order to identify improved regenerative strategies. A variety of approaches are taken, including in vitro cell and organ culture, transgenic animal models for studying gene function, in vivo models for studying periodontal repair and regeneration, and studies involving human subjects focusing on genetic disorders and pathologies affecting the dentoalveolar complex. These studies should provide greater insight on all hard and soft connective tissues, as well as help identify links between systemic conditions and the oral cavity.

Our lab's recent focus areas have been:
Role of phosphate and pyrophosphate metabolism in physiology and pathology of the dentoalveolar complex.
Role of extracellular matrix proteins and signaling molecules in development of the tooth root and differentiation of associated cell types.
Novel approaches for periodontal regeneration.


University of Minnesota, School of Dentistry
Ph.D., Oral Biology, 2013

Univ. of Minnesota, School of Dentistry
Certificate in Periodontology, 2011

Sri Siddhartha Dental College, Kamataka, India
Bachelor of Dental Surgery (B.D.S.), 2002


Clinical/Research Fellow
Laboratory of Oral and Connective Tissue Biology, NIAMS, Oct 2013–Present

Dean’s Faculty Member
University of Maryland School of Dentistry, Jan 2011–Present

Adjunct Assistant Professor
University of Minnesota, School of Dentistry, Sep 2011–Aug 2013

Dental Fellow Specialist
University of Minnesota, School of Dentistry, May 2008–May 2011

Graduate Research Assistant
University of Minnesota, School of Dentistry, Oct 2004–May 2013

Last Updated: February 2018