Research Statement

During my PhD I was focused on studying the epigenetic and transcriptional regulatory circuitries that modulate hematopoietic cell differentiation pathways with particular attention to the key role of miR-223.

During my post doc I was focused on studying the molecular players and their roles in the regulation of the three-dimensional structure and spatial organization of chromatin via long-range interactions by using cutting edge technology of genome editing and chromatin conformation captures (4C-Hi-C).

As Staff Scientist at the Translational Immunology Section I am developing cutting edge immune monitoring assays essential to determine the immune responses in patients receiving immune therapies. Moreover, I am studying the cellular and molecular target of JAK inhibitors with focus on the epigenetic modifications induced by this class of drugs on immune cells.

Education

Ph.D. in Cell Science and Morphogenesis Department of Histology and Medical Embryology, "Sapienza", University of Rome (Italy), 2010

Laurea in Genomic Biotechnologies (two-years Master degree). "Sapienza", University of Rome, 2006

Laurea in Biotechnologies. "Sapienza", University of Rome (Italy), 2004

Experience

Staff Scientist (2018 – to date) National Institute of Arthritis and Musculoskeletal and SkinDiseases (NIAMS), Translational Immunology Section

Research Fellow (2016 – 2018) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Translational Immunology Section

Post  Doctoral Fellow (2012 – 2016) National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), Genomics and Immunity Section

Post  Doctoral Fellow (2010 – 2012) “Sapienza” University of Rome, Department of Medico-Surgical Sciences and Biotechnologies, Laboratory of Neoplastic Cell Differentiation

Last Updated: March 2019