Summary

James D. Katz, M.D., is a Senior Research Physician and the director of the Rheumatology Fellowship and Training Branch. He serves as the principal investigator for several arthritis protocols. In this capacity, he is able to support the teaching mission of NIAMS toward helping to create the next generation of physician-scientists.

The adult Rheumatology Fellowship program provides training leading to ACGME-certification in Rheumatology while allowing Fellows to participate in full-scale research projects under the supervision of NIAMS or affiliated faculty during the upper years of their Fellowships.

Research Statement

The NIAMS Community Health Clinic was established in 2001 to fulfill a dual mission for the clinical program: (1) to broaden the clinical exposure of NIAMS Rheumatology Fellows, and (2) to provide an additional site for recruitment of patients from under-represented groups with rheumatic diseases to NIAMS clinical studies. 

Scientific Publications

Neutrophil-mediated carbamylation promotes articular damage in rheumatoid arthritis.

O'Neil LJ, Barrera-Vargas A, Sandoval-Heglund D, Merayo-Chalico J, Aguirre-Aguilar E, Aponte AM, Ruiz-Perdomo Y, Gucek M, El-Gabalawy H, Fox DA, Katz JD, Kaplan MJ, Carmona-Rivera C
Sci Adv.
2020 Oct;
6(44).
pii: eabd2688. doi: 10.1126/sciadv.abd2688
PMID: 33115748

Patient Perception of Disease-Related Symptoms and Complications in Relapsing Polychondritis.

Ferrada MA, Grayson PC, Banerjee S, A Sikora K, A Colbert R, Sinaii N, Katz JD
Arthritis Care Res (Hoboken).
2018 Aug;
70(8).
doi: 10.1002/acr.23492
PMID: 29245173

At the intersection of self and not-self: finding the locus of 'self' in autoimmunity.

Katz JD
Med Humanit.
2018 Jun;
44(2).
doi: 10.1136/medhum-2017-011364
PMID: 29436480

Somatic activating mutations in MAP2K1 cause melorheostosis.

Kang H, Jha S, Deng Z, Fratzl-Zelman N, Cabral WA, Ivovic A, Meylan F, Hanson EP, Lange E, Katz J, Roschger P, Klaushofer K, Cowen EW, Siegel RM, Marini JC, Bhattacharyya T
Nat Commun.
2018 Apr 11;
9(1).
doi: 10.1038/s41467-018-03720-z
PMID: 29643386

Pharmacotherapy Pearls in Rheumatology for the Care of Older Adult Patients: Focus on Oral Disease-Modifying Antirheumatic Drugs and the Newest Small Molecule Inhibitors.

Betancourt BY, Biehl A, Katz JD, Subedi A
Rheum Dis Clin North Am.
2018 Aug;
44(3).
doi: 10.1016/j.rdc.2018.03.010
PMID: 30001781

Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations.

Jha S, Fratzl-Zelman N, Roschger P, Papadakis GZ, Cowen EW, Kang H, Lehky TJ, Alter K, Deng Z, Ivovic A, Flynn L, Reynolds JC, Dasgupta A, Miettinen M, Lange E, Katz J, Klaushofer K, Marini JC, Siegel RM, Bhattacharyya T
J Bone Miner Res.
2019 Jan;
34(1).
doi: 10.1002/jbmr.3577
PMID: 30138550

Melorheostotic Bone Lesions Caused by Somatic Mutations in MAP2K1 Have Deteriorated Microarchitecture and Periosteal Reaction.

Fratzl-Zelman N, Roschger P, Kang H, Jha S, Roschger A, Blouin S, Deng Z, Cabral WA, Ivovic A, Katz J, Siegel RM, Klaushofer K, Fratzl P, Bhattacharyya T, Marini JC
J Bone Miner Res.
2019 May;
34(5).
doi: 10.1002/jbmr.3656
PMID: 30667555

Patient-perceived Burden of Disease in Pediatric Relapsing Polychondritis.

Rimland CA, Ferrada MA, Sinaii N, Sikora KA, Colbert RA, Grayson PC, Katz JD
J Rheumatol.
2019 Dec;
46(12).
doi: 10.3899/jrheum.181456
PMID: 31043550

Clinical Evaluation of Melorheostosis in the Context of a Natural History Clinical Study.

Jha S, Cowen EW, Lehky TJ, Alter K, Flynn L, Reynolds JC, Lange E, Katz JD, Marini JC, Siegel RM, Bhattacharyya T
JBMR Plus.
2019 Aug;
3(8).
doi: 10.1002/jbm4.10214
PMID: 31485554

Rheumatology capacity building: implementing a rheumatology curriculum for Liberian health-care providers in 2016.

Lewandowski LB, Schiffenbauer A, Mican JM, Moses SJ, Fallah MP, Plotz P, Katz JD
Clin Rheumatol.
2020 Mar;
39(3).
doi: 10.1007/s10067-019-04817-6
PMID: 31960207

Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway.

Kang H, Jha S, Ivovic A, Fratzl-Zelman N, Deng Z, Mitra A, Cabral WA, Hanson EP, Lange E, Cowen EW, Katz J, Roschger P, Klaushofer K, Dale RK, Siegel RM, Bhattacharyya T, Marini JC
J Exp Med.
2020 May 4;
217(5).
pii: e20191499. doi: 10.1084/jem.20191499
PMID: 32232430

Competency-based medical education for the clinician-educator: the coming of Milestones version 2.

Torralba KD, Jose D, Katz JD
Clin Rheumatol.
2020 Jun;
39(6).
doi: 10.1007/s10067-020-04942-7
PMID: 32056067

Use of Magnetic Resonance Imaging to Identify Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis.

Subedi A, Williams SG, Yao L, Maharjan S, Strauss J, Sharon E, Thomas A, Apolo AB, Gourh P, Hasni SA, Gulley JL, Kaplan MJ, Katz JD, Gupta S
JAMA Netw Open.
2020 Feb 5;
3(2).
doi: 10.1001/jamanetworkopen.2020.0032
PMID: 32101306

PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study.

Shrestha S, Kim MJ, Eldridge M, Lehmann ML, Frankland M, Liow JS, Yu ZX, Cortes-Salva M, Telu S, Henter ID, Gallagher E, Lee JH, Fredericks JM, Poffenberger C, Tye G, Ruiz-Perdomo Y, Anaya FJ, Montero Santamaria JA, Gladding RL, Zoghbi SS, Fujita M, Katz JD, Pike VW, Innis RB
J Neuroinflammation.
2020 May 2;
17(1).
doi: 10.1186/s12974-020-01804-6
PMID: 32359360

A Panoply of Rheumatological Manifestations in Patients with GATA2 Deficiency.

Amarnani AA, Poladian KR, Marciano BE, Daub JR, Williams SG, Livinski AA, Hsu AP, Palmer CL, Kenney CM, Avila DN, Holland SM, Katz JD
Sci Rep.
2020 May 20;
10(1).
doi: 10.1038/s41598-020-64852-1
PMID: 32433473

Education

Case Western Reserve University
M.D.

Experience

Program Director, Rheumatology Fellowship
Clinical Training Branch, NIAMS, NIH

Clinical Professor of Medicine
George Washington University

Division Director
George Washington University

Medicine Residency
Western Pennsylvania Hospital

Rheumatology Fellowship
University of Connecticut

Last Updated: November 2020