Summary

Fred P. Davis grew up in the American Midwest where he studied pharmacy and then found his way to the East and West coasts to study protein structure. Since landing in the Washington, D.C. area a decade ago, he has been studying how cell identity is encoded in the genome.

Research Statement

Dr. Davis’ research is driven by one central question: How does a single genome support the gene expression programs required for all the cell types in an adult animal. This question is especially exciting in the immune and nervous systems, which have many different kinds of cells. He uses genomic measurements and computation to address this question.

Scientific Publications

Developmental Acquisition of Regulomes Underlies Innate Lymphoid Cell Functionality.

Shih HY, Sciumè G, Mikami Y, Guo L, Sun HW, Brooks SR, Urban JF Jr, Davis FP, Kanno Y, O'Shea JJ
Cell.
2016 May 19;
165(5).
doi: 10.1016/j.cell.2016.04.029
PMID: 27156451

Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain.

Mo A, Mukamel EA, Davis FP, Luo C, Henry GL, Picard S, Urich MA, Nery JR, Sejnowski TJ, Lister R, Eddy SR, Ecker JR, Nathans J
Neuron.
2015 Jun 17;
86(6).
doi: 10.1016/j.neuron.2015.05.018
PMID: 26087164

Transcription factors that convert adult cell identity are differentially polycomb repressed.

Davis FP, Eddy SR
PloS one.
2013;
8(5).
doi: 10.1371/journal.pone.0063407
PMID: 23650565

Cell type-specific genomics of Drosophila neurons.

Henry GL, Davis FP, Picard S, Eddy SR
Nucleic acids research.
2012 Oct;
40(19).
doi: 10.1093/nar/gks671
PMID: 22855560

Education

Purdue University
Pharm.D., 2001

Rockefeller University
Graduate courses, Mathematical & Computational Biology, 2001 - 2003.

University of California, San Francisco
Ph.D., Biophysics, 2007

Experience

Staff Scientist
NIAMS, National Institutes of Health, 2015 – present.

Research Specialist
Howard Hughes Medical Institute, Janelia Research Campus, 2014 - 2015

Postdoctoral Fellow
Howard Hughes Medical Institute, Janelia Research Campus, 2007 - 2013

Last Updated: July 2020