Dr. Danielle Chisolm attended undergrad at Bethune-Cookman University in Daytona Beach, FL where she majored in Biology. Afterwards, she completed a post-baccalaureate program at the University of North Carolina at Chapel Hill. Dr. Chisolm then went on to complete her graduate education at the University of Alabama at Birmingham. There she worked with Amy Weinmann, where her main interest was defining novel mechanistic connections between metabolic programs and T cell differentiation gene programs.
Dr. Chisolm’s major research goals are understanding the molecular mechanisms by which different external cues regulate T cell differentiation. Many external cues are important in regulating T cell differentiation gene programs this includes, but not limited to cytokines, TCR-signaling, and metabolism. She is interested in understanding how these different cues are responsible for promoting cellular programming decisions and how this in turn is responsible in the fine tuning of an appropriate immune response. Her current focus is designing a screen using the CRISPR/Cas9 system that would allow an efficient manner of interrogating these pathways.