NIAMS Update November 2011

NIAMS - National Institute of Arthritis and Musculoskeletal and Skin Diseases
Update - An online resource for the NIAMS Coalition, Council, and Colleague
November 17, 2011
The NIAMS Update is a monthly digest published for those interested in the latest scientific news and resources on diseases of the bones, joints, muscles, and skin. We encourage further dissemination of this resource.
Contact Information

Office of Communications and Public Liaison

Anita Linde, M.P.P.
Acting Director

Melanie M. Martinez, M.P.A.
Public Liaison Officer

Trish Reynolds, R.N., M.S.
Media Liaison


Immune Cell Plays Dual Role in Allergic Skin Disease: NIH-Funded Study in Mice Enhances Understanding of Atopic Dermatitis
An immune cell involved in initiating the symptoms of an allergic skin reaction may play an equally, or perhaps more important, role in suppressing the reaction once it becomes chronic. This finding in mice could have future implications for the treatment of atopic dermatitis, a chronic inflammatory skin disease that affects an estimated 10 to 20 percent of infants and young children. The research is by investigators at the NIAMS, part of the National Institutes of Health (NIH).

NIH Study Shows Benefits, Limits of Therapy for Rare Inflammatory Syndrome
A study shows that the medication etanercept reduces the frequency and severity of symptoms of TNF receptor-associated periodic syndrome (TRAPS), a rare inherited condition characterized by recurrent fevers, abdominal pain and skin rashes. The study, published in Arthritis & Rheumatism, also points out the need for the development of additional therapies to more thoroughly ease symptoms and prevent long-term complications of the disease. The study was released by researchers at the NIAMS, a part of the NIH.

NIH Scientists Discover Link Among Spectrum of Childhood Diseases: Hard-To-Treat Disorders Characterized by Inflammation and Fat Loss
An international collaboration of scientists, including researchers at the NIAMS, has identified a genetic mutation that causes a rare childhood disease characterized predominantly by inflammation and fat loss. The research suggests that the disorder, named chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature (CANDLE), actually represents a spectrum of diseases that have been described in the literature under a variety of names. More importantly, since no effective treatment for this disease currently exists, the findings may have uncovered a possible target for future treatments.

NIH Undiagnosed Diseases Program Documents Two-Year Pilot as Clinic of Last Resort: Genomic Tools Prove Integral to Solving Medical Mysteries
After its first two years of work, the NIH's Undiagnosed Diseases Program is citing successes in patients whose cases have stumped specialists at leading medical institutions around the country. The researchers published the program's first retrospective analysis in the September 26, 2011, online issue of Genetics in Medicine.

New Go4Life Campaign Focuses on Fitness for Older Adults: Public-Private Effort Led by the NIH Reaches Out to Boomers, Their Parents
Being physically active is vital to maintaining health and independence as we age, and a new federal campaign for people age 50 and older will help them to get active and keep going. Introduced by the NIH, the Go4Life campaign encourages sedentary older adults to reap health benefits by making physical activity part of their daily lives. Only 25 percent of people age 65 to 74 say they engage in regular physical activity.

The NIH Honored for Employment of People With Disabilities
The NIH Clinical Center is the recipient of the 2011 Employer Leadership Award from the Maryland Division of Rehabilitation Services, an agency of the Maryland State Department of Education. The award is in honor of the NIH Clinical Center's pilot NIH-Project SEARCH program, in which 12 young adults with disabilities graduated from a 30-week unpaid internship in June 2011.

NIH Teacher Resources Feature Rare Diseases and Evolution
Teachers now have an innovative way to help students approach challenging biology questions with two new free curriculum supplements from the NIH: Evolution and Medicine, and Rare Diseases and Scientific Inquiry. Both supplements inform students about human health, while helping them build their problem-solving, communication, critical thinking and teamwork skills.


Save the Date: NIAMS Advisory Council Meeting
The next NIAMS Advisory Council Meeting will be held January 31, 2012, in Building 31, 6th floor, C Wing, Conference Room 6, NIH Campus.

NIH Wednesday Afternoon Lecture Series
The NIH's Wednesday Afternoon Lecture Series offers weekly lectures every Wednesday at 3 p.m. in Masur Auditorium, Building 10, NIH Campus. Renowned scientists from around the globe present research on a variety of topics. The lectures are Continuing Medical Education-certified lectures, open to the public and available live via webcast.

Upcoming lecture:

November 30, 2011
Dr. Diane E. Griffin
"Virus Clearance: It Isn't Easy"


NIH Research Matters
NIH Research Matters is a review of NIH research from the Office of Communications and Public Liaison, Office of the Director, NIH.

NIH Public Bulletin
Read about the latest public events, activities and health information resources from the NIH in the latest issue of the NIH Public Bulletin.

NIH News in Health
Read practical health information in NIH News in Health, which is reviewed by the NIH’s medical experts and is based on research conducted either by the NIH’s own scientists or by our grantees at universities and medical schools around the country.

Funding Announcements
If you would like to review information about funding opportunities more frequently than our monthly updates allow, see the NIH Guide for Grants and Contracts, the primary source for information about NIH funding opportunities. You can also request a weekly Table of Contents from the NIH Guide.