NIAMS Update April 2010

NIAMS - National Institute of Arthritis and Musculoskeletal and Skin Diseases
Update - An online resource for the NIAMS Coalition, Council, and Colleague
April 22, 2010
The NIAMS Update is a monthly digest published for those interested in the latest scientific news and resources on diseases of the bones, joints, muscles, and skin. We encourage further dissemination of this resource.
Contact Information

Office of Communications and Public Liaison

Janet S. Austin, Ph.D.

Melanie M. Martinez, M.P.A.
Public Liaison Officer

Trish Reynolds, R.N., M.S.
Media Liaison

Media Availability: A Clinical Perspective of Autoinflammatory Diseases
The science of autoinflammatory diseases has progressed rapidly since the term was first coined in the late 1990s in an effort to distinguish this distinct group of illnesses from the more well-defined autoimmune diseases, such as rheumatoid arthritis and lupus. Advances in genetic technologies have expanded the understanding of the molecular and cellular basis of autoinflammatory diseases and have broadened the field to include disorders that no longer fit within the original classification.

Soy Isoflavones Fail to Prevent Bone Loss
Researchers supported by NIAMS provided convincing evidence questioning the notion that soy isoflavone tablets can help preserve bone mineral density (BMD) in women after menopause. Their study, the longest ever to evaluate the effect of soy isoflavones on BMD, appeared recently in the American Journal of Clinical Nutrition.

Key HIV Macromolecule Structure Solved
Researchers at NIAMS and Oxford University have collaborated to determine the three-dimensional structure of Rev (regulator of virus), an essential regulatory macromolecule of HIV. Rev is a protein that escorts viral mRNA molecules out of the infected cell nucleus where they are synthesized into the cytoplasm where they are used to synthesize the building-blocks of a new generation of viral particles. If Rev is absent or is inhibited, an infection cannot proceed.

NIH Announces Genetic Testing Registry: Database to Fill Information Gaps and Serve as Research Resource
The National Institutes of Health (NIH) announced that it is creating a public database that researchers, consumers, health care providers and others can search for information submitted voluntarily by genetic test providers. The Genetic Testing Registry aims to enhance access to information about the availability, validity and usefulness of genetic tests.

Updated Exercise and Physical Activity Tips for Older Adults Now Available on NIHSeniorHealth Site
Older adults who are interested in becoming physically active, restarting a lapsed exercise regimen or getting more benefit from their current exercise program can check out the updated Exercise and Physical Activity for Older Adults topic on NIHSeniorHealth. The health and wellness Web site was designed especially for older adults by the National Institute on Aging and the National Library of Medicine, both part of NIH.

Meetings and Events
Save the Date: NIAMS Advisory Council Meeting
The next NIAMS Advisory Council Meeting will be held June 15, 2010, in Building 31, 6th floor, C Wing, Conference Room 6, NIH Campus.

NIH Wednesday Afternoon Lecture Series
NIH’s Wednesday Afternoon Lecture Series (WALS) offers weekly lectures every Wednesday at 3 p.m. in Masur Auditorium, Building 10, NIH Campus. Renowned scientists from around the globe present research on a variety of topics. The lectures are Continuing Medical Education-certified lectures, open to the public and available live via Webcast.

Upcoming lectures:

April 28, 2010
Dr. Sandra Schmid
“Protecting your Borders: Regulated Entry into the Cell”

May 5, 2010
Dr. Julie Buring
“What Do We Do When Studies Disagree?”

May 12, 2010
Dr. Joseph Takahashi
“Clock Genes and Clock Cells: A New View”

May 19, 2010
Dr. Michael Karin
“Control of Tumor Promotion and Metastatic Progression by Inflammatory Signaling”

May 20, 2010—Special Thursday Lecture
Dr. Carol Robinson
“From Rare Gases to Ribosomes”

May 26, 2010
Dr. Daniel Haber
“Interrogating Circulating Tumor Cells to Direct Targeted Cancer Therapies’

NIH Research Matters
NIH Research Matters is a review of NIH research from the Office of Communications and Public Liaison, Office of the Director, NIH.

NIH Public Bulletin
Read about the latest public events, activities and health information resources from NIH in the latest issue of the NIH Public Bulletin.

NIH News in Health
Read practical health information in NIH News in Health, which is reviewed by NIH’s medical experts and is based on research conducted either by NIH’s own scientists or by our grantees at universities and medical schools around the country.

New Publications

¿Qué es la artritis reactiva? What Is Reactive Arthritis?
A new Esenciales publication is available from NIAMS. Esenciales is a series of easy-to-read fact sheets in Spanish that describe different diseases of the bones, joints, muscles and skin, along with the diseases’ causes and treatment options. The fact sheets also provide information on current research.

Funding Announcements

Other Research Announcements

SHIFT Award: Small Businesses Helping Investigators to Fuel the Translation of Scientific Discoveries [SBIR: R43/R44]
Letters of Intent Receipt Date: Not applicable
Application Receipt Date: Standard dates apply

Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R01)
Letters of Intent Receipt Dates: Multiple dates, see announcement
Application Receipt Dates: Multiple dates, see announcement

Behavioral and Social Science Research on Understanding and Reducing Health Disparities (R21)
Letters of Intent Receipt Dates: Multiple dates, see announcement
Application Receipt Dates: Multiple dates, see announcement

Instructions for Completion and Peer Review of the Vertebrate Animal Section (VAS) in NIH Grant Applications and Cooperative Agreements

Request for Comments on Proposed NIH, AHRQ and CDC Process Change for Electronic Submission of Grant Applications

Notice of Termination of Selected Research Training and Research Career Development Award Funding Opportunity Announcements

Amended NIH Policy on Submission of Late Grant Application Materials Prior to Initial Peer Review

Enhancing Peer Review: Updated Processes for the Review of all Ruth L. Kirschstein National Research Service Award (NRSA) Fellowship Applications

NIH Will Require the Electronic Submission of Appointment Forms and Termination Notices via xTrain for Research Training, Fellowship, Education and Career Awards Beginning January 2011

Final Ruth L. Kirschstein National Research Service Award (Kirschstein-NRSA) Policy for Tuition, Fees and Health Insurance on Training Grants and Fellowships

If you would like to review information about funding opportunities more frequently than our monthly updates allow, see the NIH Guide for Grants and Contracts, the primary source for information about NIH funding opportunities. You can also request a weekly Table of Contents from the NIH Guide.