FAQs for NIAMS Centers of Research Translation (CORT) (P50)

Updated July 28, 2016

Frequently Asked Questions (FAQs) for RFA-AR-17-001: Centers of Research Translation (CORT)

  1. Question: Can a CORT focus on more than one disease?

    Answer: A CORT must focus on a single disease or a group of highly related diseases (for example, various types of epidermolysis bullosa which share a common clinical phenotype of skin blisters), although the proposed research may be relevant to more than one disease and an additional disease(s) may be used as a control if scientifically justified. Applicants are strongly encouraged to contact the Scientific/Research Contacts listed in the P50 FOA before writing the application.

  2. Question: The FOA states "Research Cores: Optional; two or more required if a single Research Project is proposed." Would it be acceptable to submit a CORT application with an Administrative Core, three Research Projects, and zero Research Cores?

    Answer: Yes.

  3. Question: Can a foreign investigator be the PI of a research project or core within a CORT application?

    Answer: Yes, but the need for the foreign component must be well justified.

  4. Question: If the PI of a research project within a P50 is a new investigator, will the person lose new investigator status if the P50 is awarded?

    Answer: According to the NIH new investigator (NI) policy (https://grants.nih.gov/grants/new_investigators/investigator_policies_faqs.htm), if the lead of a project or core in a multi-component application is a new investigator, but not the PI/PD for the overall application, the individual will retain NI status when the award is made.

  5. Question: The FOA states "Up to two Pilot & Feasibility Projects (P&Fs) may be supported for up to two years each beginning the second, third, or fourth year of the CORT funding." Is it expected that a CORT would only solicit P&Fs one time during the five-year duration of the CORT funding?

    Answer: No. A CORT could solicit P&Fs as many times as desired, but support will be provided only for a maximum of four P&F project years, with no single P&F being more than two years.

  6. Question: The FOA states that "The CORT Director is expected to make a commitment of at least 1.8 calendar months (CM) to the overall administration of the CORT plus 2.4 CM for research if the CORT director is also the lead of a CORT project. The CORT Associate Director is expected to commit at least 1.2 CM to administration." Is there an additional CM requirement for the Associate Director if he/she is also the leader of a Project or Core?

    Answer: The following requirements are described in the FOA:
    • Admin Core: The CORT Director is expected to make a commitment of at least 1.8 CM to the overall administration of the CORT, and the CORT Associate Director to commit at least 1.2 CM to administration.
    • For Research Projects: A director should be named for each Research Project. An associate director may also be proposed. The combined efforts should devote at least 2.4 CM to the project. This would be in addition to the administrative effort of the CORT Director or CORT Associate Director if either one is also a director or associate director of a project.
    • For Research Cores: A director should be named for each Research Core. An associate director may also be proposed. The combined efforts should devote at least 1.8 CM to the research core. This would be in addition to the administrative effort of the CORT Director or CORT Associate Director if either one is also a director or associate director of a research core.
  7. Question: If a CORT incorporates investigators from outside institutions for leaders of Projects/Cores, how are they handled in the budget? If they are subcontractors, do their direct costs and indirect costs come out of the total direct cost cap of $1M?

    Answer: A project or core from another institution requires a subcontract. However, consortium F&A costs are NOT included as part of the direct cost base when determining whether the application budget fits within the $1M direct cost per year limit.

  8. Question: If multi-PIs are proposed, does one need to be named as Director and the other as Associate Director, or can they be Co-Directors?

    Answer: The NIAMS strongly encourages that one be named as a Director and the other as Associate Director.