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Research
NIAMS Labs Faculty
Updated April 18, 2013
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Timothy Bhattacharyya, MD
Head, Clinical and Investigative Orthopedics Surgery Unit
Email: bhattacharyyat@mail.nih.gov
[Bio], [Lab website]
Rafael Casellas, PhD
Chief, Genomics and Immunity Section
Acting Chief, Laboratory of Molecular Immunogenetics
Adjunct Investigator, NCI
Email: casellar@mail.nih.gov
Dr. Casellas' lab main goal is to unravel the molecular mechanisms driving early development and peripheral activation of B lymphocytes.
Robert Colbert, MD, PhD
Chief, Pediatric Translational Research Branch
Email: colbertr@mail.nih.gov
The Colbert lab aims to understand the pathogenesis of chronic inflammation and its impact on structural remodeling of bone in spondyloarthritic diseases such as ankylosing spondylitis.
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Massimo Gadina PhD
Director, Office of Science and Technology
Chief, Translational Immunology Section
Email: gadinama@mail.nih.gov
Developing accurate and reproducible immune monitoring assays is essential to determine the immune responses in patients receiving novel immune therapies and ultimately transitioning these therapies from the clinical trial phase to standard of care. The goal of this section is to develop cutting edge immune monitoring technology.
Raphaela Goldbach-Mansky, MD, MHS
Acting Chief, Translational Autoinflammatory Disease Section
Email: goldbacr@mail.nih.gov
Dr. Goldbach-Mansky's research focuses on applying a systematic approach to the clinical and immunological description of a number of autoinflammatory diseases. The lab uses targeted interventions to understand the role of specific inflammatory pathways in the pathogenesis of the autoinflammatory diseases.
Mark Gourley, MD
Director, Community Research and Care Branch
Director, Clinical Care and Training
Email: gourleym@mail.nih.gov
[Bio], [Rheumatology Training Program site]
Dr. Gourley's clinical research focuses on pathogenesis and treatment of SLE and autoimmune myositis. He is dedicated for bringing care for rheumatology patients in underserved communities and promoting excellence in rheumatology education.
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Maria Morasso, PhD
Chief, Laboratory of Skin Biology
Email: morassom@mail.nih.gov
We utilize a systematic approach to understand the function of specific regulators and pathways, and a combination of mouse models, toward elucidating the molecular processes that contribute to epidermal differentiation and barrier formation, appendage development and the mechanisms underlying the pathologies of Ectodermal Dysplasias (EDs).
Leon Nesti, MD, Ph.D.
Chief, Orthopaedics Research Group
Email: nestil@mail.nih.gov
The Nesti group focuses on understanding specific orthopaedic pathologies, to better facilitate clinical transition of lab results to medical therapies.
John O'Shea, MD
Chief, Molecular Immunology and Inflammation Branch
Scientific Director, NIAMS
Email: osheajo@mail.nih.gov
Dr. O'Shea lab studies how engagement of cytokine receptors transduce signals that, in turn, regulate transcription factors and epigenetic events to modulate gene expression. Another goal is to understand how T cells participate in host defense and contribute to the pathogenesis of immune-mediated diseases.
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Evelyn Ralston, PhD
Chief, Light Imaging Section
Email: ralstone@mail.nih.gov
Our research focuses on the use of light microscopy techniques to elucidate poorly understood aspects of skeletal muscle cell biology, i.e. the organization of microtubules and their associated subcellular organelles, particularly the Golgi complex. We also strive to apply new modalities of light microscopy to the quantitative analysis of skeletal muscle pathologies.
Mahendra Rao, MD, PhD
Chief, Laboratory of Stem Cell Biology
Director, NCRM
Email: mraomah@mail.nih.gov
The goal of the lab is to use stem cells to improve our understanding of the biological processes controlling of cell fate determination and tissue development. The hope is that versatile stem cells may someday be a source of replacement cells for damaged tissues of the brain and other organs.
Juan Rivera, MSc, PhD
Chief, Molecular Immunology Section
Email: riveraj@mail.nih.gov
The work in this laboratory is directed towards understanding how allergenic agents and immune complexes activate one particular family Fc receptors and, through them, ultimately control the genes that produce the cytokines that in turn recruit other cells in the inflammatory response.
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Vittorio Sartorelli, MD
Chief, Laboratory of Muscle Stem Cells and Gene Regulation
Deputy Scientific Director, NIAMS
Email: sartorev@mail.nih.gov
We study the cellular and molecular mechanisms subtending specification, differentiation, and regeneration of skeletal muscle cells. We pursue these studies by combining cellular and molecular biological approaches, genomic and proteomic-based systems-biology, bioinformatics, and animal models.
Richard Siegel, MD, PhD
Chief, Autoimmunity Branch
Clinical Director, NIAMS
Email: siegelr@mail.nih.gov
The Siegel lab explores how alterations in regulatory signaling pathways in immune cells lead to abnormal immune responses, chronic inflammation, and autoimmune diseases. The TNF family of cytokines is the main focus of present work, as these cytokines are critical in the pathogenesis and treatment of a number of different autoimmune and inflammatory diseases.
Martha Somerman, DDS, PhD
Chief, Laboratory of Oral Connective Tissue Biology
Director, NIDCR
Email: somermanmj@mail.nih.gov
The Somerman lab studies the molecular biology of dental-oral-craniofacial development, with a focus on the periodontal complex. We aim to understand cells and signals influencing tooth, bone, and periodontal ligament development in order to identify improved regenerative strategies.
Stephen Stahl, PhD
Senior Investigator, Protein Expression Laboratory
Email: stahls1@mail.nih.gov
Dr. Stahl uses genetic manipulation techniques on bacteria to design and produce new proteins for research studies. He and his colleagues develop innovative variants of genes, altering nucleotides to tailor genes to express unique proteins in bacteria.
Alasdair Steven, PhD
Chief, Laboratory of Structural Biology Research
Email: stevena@mail.nih.gov
The Steven group seeks to elucidate structure-function-assembly relationships of macromolecular complexes by cryo-electron microscopy integrated with other approaches. Systems currently under study include viruses, cytoskeletal filaments, energy-dependent proteases, and amyloid filaments.
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Michael Ward, MD
Acting Chief, Clinical Trials and Outcomes Branch
Email: wardm1@mail.nih.gov
Our group studies health outcomes and outcome measures in patients with rheumatic diseases.
Paul Wingfield, PhD
Chief, Protein Expression Laboratory
Email: wingfiep@mail.nih.gov
The NIAMS Protein Expression Laboratory, led by Dr. Wingfield, supports intramural NIH scientists in studying the structure and function of Human Immunodeficiency Virus (HIV) proteins. Most structural biology techniques, especially those for studying the three-dimensional structures of proteins, require large quantities of highly purified, monodisperse, and correctly folded proteins.
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