Research

Light Imaging Section

Complete list of publications

Prins, K. W., Humston, J. L., Mehta, A., Tate, V., Ralston, E., & Ervasti, J. M. (2009) Dystrophin is a microtubule-associated protein. J. Cell Biol. 186, 363-9.

Zhang T., Zaal, K.J.M., Sheridan, J., Mehta, A., Gundersen, G., and Ralston, E. (2009) The Microtubule Plus-End Binding Protein EB1 is Necessary for Muscle Cell Differentiation, Elongation, and Fusion. J. Cell Sci.2009 May 1;122(Pt 9):1401-9. Epub 2009 Apr 14.

Raben, N., Baum, R., Schreiner, C., Takikita, S., Mizushima, N., Ralston, E., & Plotz, P. (2009) When More is Less, Excess and Deficiency of autophagy coexist in skeletal muscle in Pompe disease. Autophagy, 5:1, 1-3.

Raben N, Hill V, Shea L, Takikita S, Baum R, Mizushima N, Ralston E, Plotz P. Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease. Hum Mol Genet. 2008 Dec 15;17(24):3897-908. Epub 2008 Sep 9.

Ralston E, Swaim B, Czapiga M, Hwu WL, Chien YH, Pittis MG, Bembi B, Schwartz O, Plotz P, Raben N. Detection and imaging of non-contractile inclusions and sarcomeric anomalies in skeletal muscle by second harmonic generation combined with two-photon excited fluorescence. J Struct Biol. 2008 Jun;162(3):500-8. Epub 2008 Apr 8.

Raben N, Takikita S, Pittis MG, Bembi B, Marie SK, Roberts A, Page L, Kishnani PS, Schoser BG, Chien YH, Ralston E, Nagaraju K, Plotz PH. Deconstructing Pompe disease by analyzing single muscle fibers: to see a world in a grain of sand... Autophagy. 2007 Nov-Dec;3(6):546-52. Epub 2007 Jun 15.

Fukuda T, Roberts A, Ahearn M, Zaal K, Ralston E, Plotz PH, Raben N. Autophagy and lysosomes in Pompe disease. Autophagy. 2006 Oct-Dec;2(4):318-20. Epub 2006 Oct 5.

Fukuda, T., Ahearn, M., Roberts, A., Mattaliano, RJ, Zaal, K, Ralston, E, Plotz, PH, & Raben, N. Autophagy and mistargeting of therapeutic enzyme in skeletal muscle in Pompe Disease. Mol. Ther. Epub 2006 Sep 26.

Fukuda, T., Ewan, L., Bauer, M., Mattaliano, R.J., Zaal, K. J. M., Ralston, E., Plotz, P., and Raben, N. Dysfunction of endocytic and autophagic pathways in a lysosomal storage disease. Ann. Neurology 2006; 59 (4), 700-8.

Ralston, E., Lu Z., Biscocho, N., Soumaka, E., Mavroidis, M., Prats, C., Lømo, T., Capetanaki, Y. & Ploug, T. Blood vessels and desmin control the positioning of nuclei in skeletal muscle fibers. J. Cell. Physiol. Published Online: 13 Sep 2006  DOI: 10.1002/jcp.20780.

Bugnard E, Zaal KJ, Ralston E. Reorganization of microtubule nucleation during muscle differentiation. Cell Motil Cytoskeleton. 2005; 60(1): 1-13.

Shah SB, Davis J, Weisleder N, Kostavassili I, McCulloch AD, Ralston E, Capetanaki Y, Lieber RL. Structural and functional roles of desmin in mouse skeletal muscle during passive deformation. Biophys J. 2004; 86(5):2993-3008.

Ai H, Ralston E, Lauritzen HP, Galbo H, Ploug T. Disruption of microtubules in rat skeletal muscle does not inhibit insulin- or contraction-stimulated glucose transport. Am J Physiol Endocrinol Metab. 2003; 285(4):E836-44.

Lauritzen, H., Reynet, C., Ralston, E., Thomas, S., Galbo, H. and Ploug, T. Gene gun bombardment mediated expression and translocation of GFP-tagged GLUT4 in skeletal muscle fibers in vivo. Pflugers Arch. 2002 Sep;444(6):710-21

Yamazaki, T, Zaal K, Hailey D, Presley J, Lippincott-Schwartz J, Samelson L (2002). Role of Grb2 in EGF-stimulated EGFR internalization. J. Cell Sci. 115; 1791-802.

Ploug T, Ralston E. Exploring the whereabouts of GLUT4 in skeletal muscle. Mol Membr Biol. 2002; 19:39-49.

Lu Z, Joseph D, Bugnard E, Zaal KJ, Ralston E. Golgi complex reorganization during muscle differentiation: visualization in living cells and mechanism. Mol Biol Cell. 2001; 12:795-808.

Nielsen, J.N., Derave, W., Kristiansen, S., Ralston, E., Ploug, T. and Richter, E.A. (2001) Glycogen synthase localization and activity in rat skeletal muscle is strongly dependent on glycogen content. J. Physiol. London. 531, 757-769.

Ralston, E., Ploug, T., Kalhovde, J., and Lømo, T. Golgi complex, ER exit sites and microtubules in skeletal muscle fibers are organized by patterned activity. J. Neurosci. 2001; 21, 875-883.

Ralston E, Lu Z, Ploug T. The organization of the Golgi complex and microtubules in skeletal muscle is fiber type dependent. J. Neurosci. 1999; 19:10694-705

Updated January 6, 2009