Biodata Mining and Discovery Section

Extended list of publications

Callen E, Faryabi RB, Luckey M, Hao B, Daniel JA, Yang W, Sun HW, Dressler G, Peng W, Chi H, Ge K, Krangel MS, Park JH, Nussenzweig A. The DNA Damage- and Transcription-Associated Protein Paxip1 Controls Thymocyte Development and Emigration. Immunity. 2012 Nov 13. pii: S1074-7613(12)00456-6. doi: 10.1016/j.immuni.2012.10.007.

Vahedi G, Takahashi H, Nakayamada S, Sun HW, Sartorelli V, Kanno Y, O'Shea JJ. STATs Shape the Active Enhancer Landscape of T Cell Populations. Cell. 2012 Nov 21;151(5):981-93. doi: 10.1016/j.cell.2012.09.044.

Okano J, Levy C, Lichti U, Sun HW, Yuspa SH, Sakai Y, Morasso MI. Cutaneous retinoic Acid levels determine hair follicle development and downgrowth. J Biol Chem. 2012 Nov 16;287(47):39304-15. doi: 10.1074/jbc.M112.397273. Epub 2012 Sep 24.

Hirahara K, Ghoreschi K, Yang XP, Takahashi H, Laurence A, Vahedi G, Sciumè G, Hall AO, Dupont CD, Francisco LM, Chen Q, Tanaka M, Kanno Y, Sun HW, Sharpe AH, Hunter CA, O'Shea JJ. Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1. Immunity. 2012 Jun 21. [Epub ahead of print]

Baba M, Keller JR, Sun HW, Resch W, Kuchen S, Suh HC, Hasumi H, Hasumi Y, Kieffer-Kwon KR, Gonzalez CG, Hughes RM, Klein ME, Oh HF, Bible P, Southon E, Tessarollo L, Schmidt LS, Linehan WM, Casellas R. The Folliculin-FNIP1 pathway deleted in human Birt-Hogg-Dube syndrome is required for mouse B cell development. Blood. 2012 Jun 18. [Epub ahead of print]

Zhu BM, Kang K, Yu JH, Chen W, Smith HE, Lee D, Sun HW, Wei L, Hennighausen L. Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes. Nucleic Acids Res. 2012 May;40(10):4461-72. doi: 10.1093/nar/gks056.

Duverger O, Zah A, Isaac J, Sun HW, Bartels AK, Lian JB, Berdal A, Hwang J, Morasso MI. Neural crest deletion of Dlx3 leads to Major Dentin defects through downregulation of Dspp. J Biol Chem. 2012 Feb 20. [Epub ahead of print]

Nakayamada S, Kanno Y, Takahashi H, Jankovic D, Lu KT, Johnson TA, Sun HW, Vahedi G, Hakim O, Handon R, Schwartzberg PL, Hager GL, O'Shea JJ. Early Th1 Cell Differentiation Is Marked by a Tfh Cell-like Transition. Immunity. 2011 Dec 23;35(6):919-31.

Lu KT, Kanno Y, Cannons JL, Handon R, Bible P, Elkahloun AG, Anderson SM, Wei L, Sun H, O'Shea JJ, Schwartzberg PL. Functional and Epigenetic Studies Reveal Multistep Differentiation and Plasticity of In Vitro-Generated and In Vivo-Derived Follicular T Helper Cells.Immunity. 2011 Oct 19.

Stojanov S, Lapidus S, Chitkara P, Feder H, Salazar JC, Fleisher TA, Brown MR, Edwards KM, Ward MM, Colbert RA, Sun HW, Wood GM, Barham BK, Jones A, Aksentijevich I, Goldbach-Mansky R, Athreya B, Barron KS, Kastner DL. Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) is a disorder of innate immunity and Th1 activation responsive to IL-1 blockade. Proc Natl Acad Sci U S A. 2011 Apr 8

Yang XP, Ghoreschi K, Steward-Tharp SM, Rodriguez-Canales J, Zhu J, Grainger JR, Hirahara K, Sun HW, Wei L, Vahedi G, Kanno Y, O'Shea JJ, Laurence A. Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5. Nature Immunology. 2011 Mar;12(3):247-54.

Yamane A, Resch W, Kuo N, Kuchen S, Li Z, Sun HW, Robbiani DF, McBride K, Nussenzweig MC, Casellas R. Deep-sequencing identification of the genomic targets of the cytidine deaminase AID and its cofactor RPA in B lymphocytes. Nature Immunology 2011 Jan;12(1):62-9.

Ghoreschi K, Laurence A, Yang XP, Tato CM, McGeachy MJ, Konkel JE, Ramos HL, Wei L, Davidson TS, Bouladoux N, Grainger JR, Chen Q, Kanno Y, Watford WT, Sun HW, Eberl G, Shevach EM, Belkaid Y, Cua DJ, Chen W, O'Shea JJ. Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling. Nature. 2010 Oct 21;467(7318):967-71.

Daniel JA, Santos MA, Wang Z, Zang C, Schwab KR, Jankovic M, Filsuf D, Chen HT, Gazumyan A, Yaname A, Cho YW, Sun HW, Ge K, Peng W, Nussenzweig MC, Casellas R, Dressler GR, Zhao K, Nussenzweig A. PTIP promotes chromatin changes critical for immunoglobulin class switch recombination. Science 2010 Aug 20;329(5994):917-23.

Kuchen S, Resch W, Yamane A, Kuo N, Li Z, Chakraborty T, Wei L, Laurence A, Yasuda T, Peng S, Hu-Li J, Lu K, Dubois W, Kitamura Y, Charles N, Sun HW, Muljo S, Schwartzberg PL, Paul WE, O'Shea J, Rajewsky K, Casellas R. Regulation of microRNA expression and abundance during lymphopoiesis. Immunity. 2010 Jun 25;32(6):828-39.

Wei G, Wei L, Zhu J, Zang C, Hu-Li J, Yao Z, Cui K, Kanno Y, Roh TY, Watford WT, Schones DE, Peng W, Sun HW, Paul WE, O'Shea JJ, Zhao K. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells. Immunity. 2009 Jan;30(1):155-67.

*Souto-Carneiro MM, *Longo NS, *Russ DE, Sun HW, Lipsky PE. Characterization of the Human Ig Heavy Chain Antigen Binding Complementarity Determining Region 3 Using a Newly Developed Software Algorithm, JOINSOLVER. J Immunol. 2004; 172(11): 6790-6802. *First authorship was shared among these contributors.

Higuchi T, Orita T, Nakanishi S, Katsuya K, Watanabe H, Yamasaki Y, Waga I, Nanayama T, Yamamoto Y, Munger W, Sun HW, Falk RJ, Jennette JC, Alcorta DA, Li H, Yamamoto T, Saito Y, Nakamura M. Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney. J Biol Chem. 2004 Jan 16;279(3):1968-79. Epub 2003 Oct 17.Click here to read

Waga I, Yamamoto J, Sasai H, Munger WE, Hogan SL, Preston GA, Sun HW, Jennette JC, Falk RJ, Alcorta DA. Altered mRNA expression in renal biopsy tissue from patients with IgA nephropathy. Kidney Int. 2003 Oct;64(4):1253-64.

Swope M, Sun HW, Blake PR, Lolis E. Direct link between cytokine activity and a catalytic site for macrophage migration inhibitory factor. EMBO J. 1998 Jul 1;17(13):3534-41.

Swope MD, Sun HW, Klockow B, Blake P, Lolis E. Macrophage migration inhibitory factor interactions with glutathione and S-hexylglutathione. J Biol Chem. 1998 Jun 12;273(24):14877-84.

Sun HW, Swope M, Cinquina C, Bedarkar S, Bernhagen J, Bucala R, Lolis E. The subunit structure of human macrophage migration inhibitory factor: evidence for a trimer. Protein Eng. 1996 Aug;9(8):631-5.

Sun HW, Bernhagen J, Bucala R, Lolis E. Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5191-6.

Sun HW, Lolis E. Salvaging recombinants from low-efficiency ligase reactions for more efficient subcloning. Biotechniques. 1995 Apr;18(4):644-6, 648, 650.

Green DW, Sun HW, Plapp BV. Inversion of the Substrate Specificity of Yeast Alcohol Dehydrogenase. J Biol Chem. 1993 Apr 15;268(11):7792-8.

Plapp BV, Green DW, Sun HW, Park DH, Kim K. Substrate specificity of alcohol dehydrogenases. Adv Exp Med Biol. 1993;328:391-400.

Sun HW, Plapp BV. Progressive Sequence Alignment and Molecular Evolution of the Zn-containing Alcohol Dehydrogenases. J Mol Evol. 1992 Jun;34(6):522-35.

Updated December 11, 2012